CBCT Vs OPT on the Oral Health Status At 12 Months of Patients Hospitalized for Infective Endocarditis.

Launched by NANTES UNIVERSITY HOSPITAL · Feb 13, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how effective a special type of dental imaging called Cone Beam Computed Tomography (CBCT) is compared to a traditional dental X-ray (Orthopantomogram or OPT) in checking the oral health of patients who have a serious infection called Infective Endocarditis (IE). This infection can lead to severe health problems, and some patients may have hidden infections in their mouths that could make the situation worse. The trial aims to see if using CBCT can help find these hidden oral infections better than the traditional method, potentially improving patient care and reducing the chances of new infections.

To participate in this study, patients must be over 18 years old and currently hospitalized for Infective Endocarditis, regardless of the specific bacteria causing their infection. They should also have a stable health condition that allows for dental imaging and expect to live for at least six more months. If eligible, participants will undergo both types of imaging during their hospital stay and may need to visit the dental department for further treatment if any oral infections are found. This trial is important because it could lead to better detection of oral health issues in patients with IE, ultimately improving their overall health outcomes.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients hospitalized for definite IE according to the 2015 ESC classification, whatever the IE responsible microorganism;
• • 2. Patients with a stable clinical state compatible with the performance of an OPT and a CBCT during his/her initial hospitalization for acute IE management;
• • 3. Patients whose life expectancy is expected to be longer than 6 months;
• • 4. Patients who agree to visit the dental department of the hospital to carry out OIF eradication or at his/her personal dentist;
• • 5. Patients over 18 years old;
• • 6. Patients affiliated to a Social Security or a health insurance scheme;
• • 7. Patients who have given informed consent to participate to the study.
• Exclusion Criteria:
• • 1. OPT or CBCT already performed before the inclusion of the patients in the study and available for the investigator during the patient's hospitalization.
• • 2. Medical contraindications to perform OPT or CBCT imaging;
• • 3. Absence of microbiologic identification of the IE responsible microorganism;
• • 4. Pregnant or breastfeeding women;
• • 5. Patients unable to give informed consent to participate to the study (under trusteeship, guardianship and legal protection).