The COSP-RBD Study: Concussions and Contact Sports in RBD vs Controls

Launched by GUY'S AND ST THOMAS' NHS FOUNDATION TRUST · Feb 13, 2024

Keywords

ClinConnect Summary

The COSP-RBD Study is looking into the relationship between concussions, contact sports, and a condition called REM Sleep Behavior Disorder (RBD). RBD can cause people to act out their dreams, and researchers want to find out how many people with RBD have had concussions or played contact sports compared to those without RBD. This study is important because it could help us understand if there’s a connection between these factors and RBD.

To participate, you need to be at least 50 years old and have either a diagnosis of RBD or be part of the control group that does not have RBD. Participants will meet with a sleep medicine specialist who will ask questions about any history of concussions and involvement in contact sports. The study is currently recruiting participants, and it aims to gather important information that could lead to better understanding and treatment of RBD in the future. If you’re interested in how your experiences might contribute to this research, this could be a valuable opportunity.

Gender

ALL

Eligibility criteria

• Inclusion criteria group with RBD:
• • Patient at the SDC with diagnosis of RBD (Guy's and St Thomas' NHS Foundation Trust).
• • 50 years of age or above (patients below this age would not be expected to have a RBD related to a synucleinopathy and other causes of RBD would need to be considered instead - e.g. narcolepsy, post-traumatic stress disorder).
• Inclusion criteria control group:
• • Patients who have undergone a v-PSG at the SDC (Guy's and St Thomas' NHS Foundation Trust) and who do not have history of suspected RBD or RBD confirmed by v-PSG.
• • 50 years of age or above This group will be age- and sex-matched to the RBD group.
• Exclusion criteria group with RBD:
• • Age \< 50 years of age.
• • Diagnoses of narcolepsy or post-traumatic stress disorder.
• • Subjects lacking capacity or literacy.
• • Non-English speakers.
• Exclusion criteria control group:
• • Age \< 50 years of age (in order to match RBD group).
• • REM sleep without atonia or confirmed RBD on v-PSG.
• • Diagnosis of neurological diseases, cognitive complaints or motor complaints.
• • Clinical history suggestive of parasomnia that may be included in the differential of RBD.
• • Subjects lacking capacity or literacy.
• • Non-English speakers.