Effects of Exercise Training in Survivors of Lymphoma

Launched by NORWEGIAN SCHOOL OF SPORT SCIENCES · Feb 13, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how different types of exercise can help people who have survived lymphoma, particularly those who received a specific type of chemotherapy called anthracyclines. Researchers want to see if aerobic exercise (like running or swimming) alone or combined with resistance training (like lifting weights) can improve health compared to those who don’t have a history of cancer. They are looking for participants who have completed their lymphoma treatment within the last two to five years and are not experiencing severe fatigue.

To join the study, participants need to be between 18 and 75 years old, have a confirmed lymphoma diagnosis, and not be currently active in more than 75 minutes of aerobic exercise per week. Those who are eligible can expect to engage in a structured exercise program and monitor their health alongside a supportive team. It's important to note that individuals with a history of cancer relapse, certain heart conditions, or those unable to understand the study procedures in Swedish or Norwegian are not eligible to participate.

Gender

ALL

Eligibility criteria

• Inclusion Criteria Lymphoma participants:
• • Listed in relevant registers
• • Confirmed lymphoma diagnosis (i.e., Hodgkin lymphoma and aggressive non-Hodgkin lymphoma)
• • Completed treatment in the past two to five years without relapse or second cancer
• • Previous anthracycline treatment with or without mediastinal radiation
• • No severe cancer-related fatigue (per self-report)
• Inclusion Criteria Lymphoma participants and non-cancer reference group:
• • Currently not performing \>75 minutes/week of aerobic exercise
• • Willing and able to adhere to all study procedures.
• Exclusion Criteria Lymphoma participants:
• • Relapse since diagnosis
• • A history, or current presence, of another diagnosis of invasive cancer of any kind
• Exclusion Criteria Lymphoma participants and non-cancer reference group:
• • Presence of any uncontrolled- or recent cardiovascular disease
• • Has undergone heart surgery
• • Uses a pacemaker
• • Pregnancy
• • Unable to read and understand Swedish (applicable for the Swedish site only)
• • Unable to read and understand Norwegian (applicable for the Norwegian site)
• • Any physical or mental health condition restricting adherence to study protocol