Intramuscular Midazolam Versus Intravenous Diazepam for Acute Seizure in Children

Launched by AROOJ KHAN · Feb 14, 2024

Keywords

ClinConnect Summary

A seizure or convulsion is a time-limited, paroxysmal, change in motor activity and or behavior that results from electrical activity in the brain that is abnormal.1 The emergency department of a hospital is usually the place where children with seizures receive first treatment and medical support. Seizures make up about 1% of all emergency department visits for pediatric patients, and at least 5% of pediatric patients will have a seizure by the time they are 16 years old. Children younger than one year of age are commonly affected by new and unprovoked seizures.2 Seizures can result in con...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients presented to the pediatric emergency, with all types of seizures, aged 3 months to 5 years.
• Exclusion Criteria:
• • 1. Children who already had intravenous access. 2. Children who had signs of clinical heart failure like tachycardia, tachypnea, and hepatomegaly.
• • 3. Children who had any severe systemic disease like renal disorder, liver disorder, and Beta Thalassemia major.
• • 4. Known allergy to midazolam or diazepam 5. Children who had hypoglycemia as the known cause of seizure 6. Children with other known causes of fits, like hypocalcemia, CKD, Hypoparathyroidism, Renal Tubular Acidosis