Comparison Between Optical Coherence Tomography and Intravascular Ultrasound for Intermediate Left Main Coronary Artery Lesions

Launched by FUNDACIÓN EPIC · Feb 14, 2024

Keywords

ClinConnect Summary

This clinical trial is comparing two imaging techniques—Optical Coherence Tomography (OCT) and Intravascular Ultrasound (IVUS)—to better understand and evaluate certain types of heart artery blockages, specifically in the left main coronary artery (LMCA). This artery is crucial for heart health, and the trial aims to see how well each technique can measure the size of artery openings in patients with moderate blockages. The study will help doctors determine which imaging method provides the best insights for guiding treatment decisions.

To participate, individuals need to be at least 18 years old and have a specific type of blockage in the LMCA that shows between 25% and 60% narrowing. Participants must also be able to give their consent to join the study. During the trial, participants will undergo imaging tests using both IVUS and OCT to gather data on their artery conditions. It's important to note that people with certain heart conditions or previous surgeries may not be eligible. This trial is currently recruiting participants, and it could lead to better ways of assessing and treating heart disease in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients aged ≥18 years
• • Patients with intermediate lesion in the LMCA (Left Main Coronary Artery) (25-60% angiographic stenosis by visual estimation) in whom a study with intracoronary imaging technique is considered (at least one pullback with IVUS (Intravascular ultrasound) and OCT (OPTICAL COHERENCE TOMOGRAPHY) from one of the main branches is mandatory).
• • Patients able to give informed consent form.
• Exclusion Criteria:
• • Patients with indication for coronary surgery regardless of significance of LMCA lesion.
• • Patients with LMCA lesion showing ulceration, dissection or thrombus.
• • Patients with lesion in a previous functioning arterial or venous graft in the territory supplied by the LMCA (protected LMCA).
• • Patients with acute coronary syndrome with potentially culpable injury in LMCA.
• • Patients unable to give informed consent.
• • Patients with ostial LMCA lesion.