Effect of Lipikar Urea 30% Before Actinic Keratoses Treatment

Launched by COSMETIQUE ACTIVE INTERNATIONAL · Feb 16, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a cream called Lipikar Urea 30% on adults with actinic keratoses, which are rough patches on the scalp caused by sun damage. The goal is to see how well this cream works in combination with a specific treatment called Tolak® in improving the skin’s condition, tolerance to treatment, and overall appearance of the lesions. The study is currently recruiting participants aged 65 to 74 who have at least four mild to moderate actinic keratosis lesions on their scalp and are planning to receive treatment with Tolak®.

To be eligible for this study, participants must not have had any treatments for their actinic keratosis in the past three months, must not be allergic to the ingredients in the creams, and should not have any serious skin issues in the treatment area. If you join the study, you can expect regular check-ins to monitor your skin's response to the treatment and to assess any side effects. This trial is important because it aims to find a better way to manage and treat actinic keratoses, potentially improving the quality of life for those affected.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • diagnosis of at least 4 non-hypertrophic, non-hyperkeratotic actinic keratosis of the the scalp
• • planned treatment of actinic keratoses of the scalp with Tolak®
• • Olsen grade I or II
• Exclusion Criteria:
• • known or documented intolerance to any of the ingredients of Tolak® or Lipikar Urea 30%
• • treatment of actinic keratoses in the treatment area within the past 3 months (e.g. photodynamic therapy, topical 5-FU, diclofenac, imiquimod, cryotherapy etc.)
• • suspected invasive squamous cell cancer in the treatment area
• • chronic wounds, erosions, pre-existing inflamed or infected skin with disruption of the epidermal barrier in the treatment area current or within the last 8 weeks given systemic cancer medication or systemic treatment with 5-Fluorouracil