H. Pylori Screen-and-treat Study in a Population of Young Adults

Launched by UNIVERSITY OF LATVIA · Feb 16, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how screening and treating an infection called H. pylori can help prevent gastric cancer, especially in young adults. Gastric cancer is a significant health concern globally, and H. pylori infection is linked to many of these cases. The trial will involve about 6,800 adults aged 30-34 from countries like Ireland, Croatia, Latvia, Poland, Romania, and Slovenia. Participants will be tested for the infection, and if found positive, they will receive treatment as per medical guidelines. The goal is to understand how effective and acceptable this screening and treatment approach is in preventing gastric cancer.

To be eligible for this study, participants should be young adults aged between 30 and 34. Those who have previously been treated for an H. pylori infection or have had surgery on their stomach for any reason cannot take part. Participants will be asked to share some information about their early childhood risk factors and habits like alcohol and tobacco use. Throughout the study, researchers will monitor how well participants follow the testing and treatment process, any side effects they might experience, and the reasons for anyone dropping out. The findings from this trial will be shared with both the public and medical communities to help improve strategies for preventing gastric cancer in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Young adults (generally 30 - 34 years of age)
• Exclusion Criteria:
• • Patients with mental or developmental limitations who cannot provide a fully-informed consent to participate (based on the assessment from research or patient's personal physician team)
• • Previously treated H. pylori infection
• • History of partial or total gastric resection due to benign or malign lesions