HONEY for the Treatment of POst-Tonsillectomy Pain

Launched by EAST AND NORTH HERTFORDSHIRE NHS TRUST · Feb 16, 2024

Keywords

ClinConnect Summary

This clinical trial, called HONEY for the Treatment of Post-Tonsillectomy Pain, is studying whether Manuka honey can help reduce pain after a tonsillectomy, a surgery to remove the tonsils. Researchers want to see if using honey, along with standard pain relief methods, is more effective than using a placebo (a treatment that looks like the real thing but has no active ingredients) along with standard pain relief. The goal is to find a low-cost, natural option for pain management that might work better for patients recovering from this surgery.

To participate in the trial, you need to be an adult, at least 18 years old, and scheduled for a bilateral tonsillectomy (surgery on both tonsils). However, certain people cannot join, such as those with specific health conditions like diabetes or a history of certain cancers, as well as children and pregnant individuals. If you choose to participate, you can expect to receive either Manuka honey or a placebo in addition to the usual pain relief medication after your surgery. The trial is currently recruiting participants, and it hopes to provide valuable information about the use of honey for managing pain after tonsil surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adult (≥18years old at the time of giving consent)
• • Consented and listed for bilateral tonsillectomy or adenotonsillectomy
• • Tonsillectomy performed within the trial study period
• Exclusion Criteria:
• • Any concurrent Head \& Neck (H\&N) malignancy
• • Unilateral tonsillectomy
• • Pregnancy
• • Concurrent pharyngeal or upper aerodigestive tract biopsy
• • Robotic tonsillectomy
• • Previous H\&N malignancy
• • Previous H\&N radiotherapy
• • Type 1/2 diabetes mellitus
• • Known allergy to bee related products
• • Known allergy to golden syrup
• • History of chronic pain
• • History of fibromyalgia
• • Current usage of chronic (\>6weeks) analgesia
• • High-risk anaesthetic patients
• • Children or adolescents \<18years old
• • Adults unable to consent for themselves