Nebulized Salbutamol in Acute Renal Colic

Launched by OMAN MEDICAL SPECIALITY BOARD · Feb 17, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a medication called nebulized salbutamol for treating pain caused by renal colic, which is intense pain often due to kidney stones. Researchers want to see if nebulized salbutamol can help reduce pain better than a placebo (a treatment without active medication) when given to patients in the emergency department. The trial will involve about 200 adults aged 18 to 60 who come to the emergency room with symptoms of renal colic. To participate, individuals must be stable and able to understand the study and consent to join.

Participants in the trial will receive either 10 mg of nebulized salbutamol or a saline solution, along with standard pain relief treatment. Their pain levels will be measured at different times after the treatment, and the researchers will also keep track of any side effects or need for additional pain relief. This study aims to find out if nebulized salbutamol is an effective and safe option for managing renal colic pain. It’s important to know that certain health conditions, like allergies to salbutamol or severe liver or kidney issues, would exclude someone from participating in this trial.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patient with classical acute renal colic symptoms.
• • 2. Age ≥ 18 years and \< 60 years
• • 3. Hemodynamically stable vital signs.
• • 4. Mentally competent patient who can understand and sign the consent form.
• Exclusion Criteria:
• • 1. Patients who are allergic to Salbuamtol.
• • 2. Renal disease or transplant.
• • 3. Patients with pervious myocardial infarction and PCI.
• • 4. Active peptic ulcer disease.
• • 5. Liver cirrhosis.
• • 6. Couagulopathy.
• • 7. History of asthma , urticaria, or other allergic-type reactions after taking NSAIDs.
• • 8. Patient with any other contraindications to use of NSAIDs.