Physical Therapy in Patients Undergoing Allo-HSCT With cGVHD

Launched by UNIVERSITY OF SEVILLE · Feb 25, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how physical therapy can help patients who have undergone a specific type of stem cell transplant and are dealing with a condition called chronic graft-versus-host disease (cGVHD). cGVHD can cause various health challenges and affect the quality of life for these patients. The goal of the study is to see if adding physical therapy, which includes exercises to improve muscle strength and endurance, can make a positive difference in their health and well-being.

To participate in this trial, you need to be an adult (18 years or older) who has received an allogeneic hematopoietic stem cell transplant and has been diagnosed with cGVHD. You should not have any serious health issues that would prevent you from exercising, and you need to be comfortable using the internet and speak Spanish. Participants will be asked to engage in physical therapy sessions and will undergo assessments at the beginning and end of the trial to evaluate their progress. This study aims to fill a gap in research regarding the benefits of physical therapy for patients with cGVHD, and it could help improve care for others in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• * Patients with chronic Graft-Versus-Host Disease (cGVHD) treated at Virgen del Rocío University Hospital will be invited to participate in the trial (n=108), under the following eligibility criteria: Inclusion criteria:
• • Adult (18 years or older); Underwent allogeneic hematopoietic stem cell transplantation (alloHSCT) diagnosed with cGVHD; No medical contraindication for moderate or high-intensity exercise; Proficiency in the Spanish language; Have access to the internet.
• Exclusion Criteria:
• • Unable to perform initial or final physical assessments; Having serious pre-existing conditions before the oncological diagnosis or diseases that are not or poorly controlled; Not signing or delivering the informed consent on the indicated date.