BRING-UP 3 Heart Failure
Launched by HEART CARE FOUNDATION · Feb 19, 2024
Trial Information
Current as of June 27, 2025
Recruiting
Keywords
ClinConnect Summary
The BRING-UP 3 Heart Failure trial is an observational study designed to understand how well patients with heart failure are being treated according to current medical guidelines. Specifically, it focuses on patients with Heart Failure with Reduced Ejection Fraction (HFrEF), which means their heart isn't pumping blood as effectively as it should. The study aims to see how safe these treatments are, how doctors are managing patients with acute heart failure (sudden worsening of symptoms), and to look at treatment patterns in all patients with chronic heart failure, regardless of their heart function levels.
To participate in this study, individuals must be at least 18 years old and can be of any gender. They should have heart failure, whether it's a new case or a worsening of an existing condition. Participants will need to provide consent to join the study. However, those with certain serious health issues or who are already taking part in other studies will not be eligible. By joining this trial, participants can help researchers gather valuable information that may improve heart failure care for others in the future.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. Age ≥18 years old.
- • 2. Males and females at birth.
- • 3. Any ejection fraction level (level of ejection fraction measured in the 6 months preceding enrollment).
- • 4. Ambulatory chronic HF or Hospitalized de-novo or worsening HF.
- • 5. Signed informed consent
- • Diagnosis will be made by the local attending physician following the ESC guidelines recommendations.
- Exclusion Criteria:
- • 1. Active neoplasia or very severe disease compromising short-medium term life expectancy.
- • 2. Participation in interventional studies.
- • 3. Patients already enrolled into the study from another participating center or in the previous enrolling phase.
About Heart Care Foundation
The Heart Care Foundation is a leading nonprofit organization dedicated to advancing cardiovascular health through innovative research and clinical trials. Committed to enhancing patient outcomes, the Foundation collaborates with medical institutions and experts to explore cutting-edge therapies and interventions for heart-related conditions. By fostering a multidisciplinary approach and prioritizing patient-centered care, the Heart Care Foundation aims to contribute significantly to the understanding and treatment of cardiovascular diseases, ultimately improving the quality of life for individuals affected by these conditions.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Ancona, An, Italy
Bari, Ba, Italy
Brindisi, Br, Italy
Gavardo, Bs, Italy
San Fermo Della Battaglia, Co, Italy
Catania, Ct, Italy
Lecco, Lc, Italy
Sesto San Giovanni, Mi, Italy
Vittoria, Rg, Italy
Roma, Rm, Italy
Rimini, Rn, Italy
Poggibonsi, Si, Italy
Augusta, Sr, Italy
Saronno, Va, Italy
San Bonifacio, Vr, Italy
Casale Monferrato, Al, Italy
Avellino, Av, Italy
Altamura, Ba, Italy
Paola, Cs, Italy
Sassuolo, Mo, Italy
Olbia, Ot, Italy
Monselice, Pd, Italy
Foligno, Pg, Italy
Roma, Rm, Italy
Tivoli, Rm, Italy
Eboli, Sa, Italy
Vallo Della Lucania, Sa, Italy
Avola, Sr, Italy
Tradate, Va, Italy
Santorso, Vi, Italy
Borgomanero, , Italy
Napoli, , Italy
Palermo, Pa, Italy
Napoli, , Italy
Bologna, Bo, Italy
Firenze, Fi, Italy
Pisa, Pi, Italy
San Giovanni Rotondo, Fg, Italy
San Donato Milanese, Mi, Italy
Rieti, Ri, Italy
Roma, Rm, Italy
Taranto, Ta, Italy
Trento, Tn, Italy
Vercelli, Vc, Italy
Mondovì, Cn, Italy
Savigliano, Cn, Italy
Castrovillari, Cs, Italy
Novi Ligure, Al, Italy
Arezzo, Ar, Italy
Cortona, Ar, Italy
Acquaviva Delle Fonti, Ba, Italy
Bari, Ba, Italy
Bari, Ba, Italy
Monopoli, Ba, Italy
Ponderano, Bi, Italy
Feltre, Bl, Italy
Bentivoglio, Bo, Italy
Bologna, Bo, Italy
Desenzano Del Garda, Bs, Italy
Lumezzane, Bs, Italy
Barletta, Bt, Italy
Bolzano, Bz, Italy
Caserta, Ce, Italy
Castel Morrone, Ce, Italy
Maddaloni, Ce, Italy
Chieti, Ch, Italy
Cuneo, Cn, Italy
Casalmaggiore, Cr, Italy
Catania, Ct, Italy
Catanzaro, Cz, Italy
Forli', Fc, Italy
Ferrara, Fe, Italy
Foggia, Fg, Italy
Gorizia, Go, Italy
Monfalcone, Go, Italy
Copertino, Le, Italy
Lecce, Le, Italy
Scorrano, Le, Italy
Livorno, Li, Italy
Camaiore, Lu, Italy
Policoro, Matera, Italy
Desio, Mb, Italy
Vimercate, Mb, Italy
Macerata, Mc, Italy
Messina, Me, Italy
Messina, Me, Italy
Cernusco Sul Naviglio, Mi, Italy
Milano, Mi, Italy
Milano, Mi, Italy
Milano, Mi, Italy
Milano, Mi, Italy
Milano, Mi, Italy
Mirandola, Mo, Italy
Cefalu', Pa, Italy
Palermo, Pa, Italy
Palermo, Pa, Italy
Palermo, Pa, Italy
Palermo, Pa, Italy
Castel San Giovanni, Pc, Italy
Piacenza, Pc, Italy
Pescara, Pe, Italy
Citta' Di Castello, Pg, Italy
Gubbio, Pg, Italy
San Vito Al Tagliamento, Pn, Italy
Fidenza, Pr, Italy
Pavia, Pv, Italy
Voghera, Pv, Italy
Lugo, Ra, Italy
Ravenna, Ra, Italy
Guastalla, Re, Italy
Reggio Emilia, Re, Italy
Ariccia, Rm, Italy
Civitavecchia, Rm, Italy
Roma, Rm, Italy
Roma, Rm, Italy
Roma, Rm, Italy
Roma, Rm, Italy
Roma, Rm, Italy
Salerno, Sa, Italy
Salerno, Sa, Italy
Siena, Si, Italy
Sarzana, Sp, Italy
Sassari, Ss, Italy
Pietra Ligure, Sv, Italy
Orbassano, To, Italy
Torino, To, Italy
Trieste, Ts, Italy
Udine, Ud, Italy
Castellanza, Va, Italy
Mestre, Ve, Italy
Noale, Ve, Italy
Arzignano, Vi, Italy
Viterbo, Vt, Italy
Gattico, , Italy
Matera, , Italy
Napoli, , Italy
Napoli, , Italy
Novara, , Italy
Pozzuoli, , Italy
Ancona, An, Italy
Carbonara Di Bari, Ba, Italy
Brescia, Bs, Italy
Canosa Di Puglia, Bt, Italy
Verduno, Cn, Italy
Catania, Ct, Italy
Catanzaro, Cz, Italy
Enna, En, Italy
Cento, Fe, Italy
Lagosanto, Fe, Italy
Empoli, Fi, Italy
Firenze, Fi, Italy
Firenze, Fi, Italy
Genova, Ge, Italy
Genova, Ge, Italy
Lavagna, Ge, Italy
Massa Marittima, Gr, Italy
Piombino, Li, Italy
Castelnuovo Di Garfagnana, Lu, Italy
Monza, Mb, Italy
Bergamo, Mi, Italy
Cinisello Balsamo, Mi, Italy
Legnano, Mi, Italy
Milano, Mi, Italy
Milano, Mi, Italy
Milano, Mi, Italy
Paderno Dugnano, Mi, Italy
Passirana, Mi, Italy
Rozzano, Mi, Italy
Matera, Mount, Italy
Policoro, Mount, Italy
Palermo, Pa, Italy
Perugia, Pg, Italy
Pontedera, Pi, Italy
Pistoia, Point, Italy
Pavia, Pv, Italy
Roma, Rm, Italy
Roma, Rm, Italy
San Gavino Monreale, Su, Italy
Savona, Sv, Italy
Chivasso, To, Italy
Cirié, To, Italy
Ivrea, To, Italy
Torino, To, Italy
Torino, To, Italy
Torino, To, Italy
Rovereto, Trento, Italy
Civita Castellana, Vt, Italy
Lacco Ameno, , Italy
Napoli, , Italy
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported