Efficacy Of Hiatal Closure For GERD

Launched by UNIVERSITY OF CHICAGO · Feb 19, 2024

Keywords

ClinConnect Summary

This clinical trial is designed to investigate the effectiveness of a surgical procedure called hiatal closure for treating gastroesophageal reflux disease (GERD) in early stages. GERD is a condition where stomach acid frequently flows back into the esophagus, causing discomfort and other symptoms. The research team believes that repairing a hiatal defect, which is a small opening in the diaphragm that can contribute to GERD, could be a helpful solution for patients experiencing this condition.

To participate in the trial, individuals need to be between 18 and 50 years old, have a body mass index (BMI) under 30, and show specific signs of GERD based on pH testing. Participants will undergo a surgical procedure if they qualify, and they will be monitored throughout the study to assess the treatment's success. It's important to note that individuals who are children, pregnant, or in vulnerable situations, like prisoners, will not be eligible for this study. If you're considering participating, it could be a chance to help improve treatment options for GERD while receiving care for your condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age 18 - 50 years
• • Able to provide informed consent
• • BMI \<30
• • Hiatal defect \<4cm on esophagram
• • pH testing requirement: pH \<4 for \>5.5%
• • Surgical candidate for hiatal closure only
• Exclusion Criteria:
• • Vulnerable subjects (children, prisoners, pregnant women) will be excluded.