GreenBladder - Early Detection of Bladder Cancer in Residents in Greenland Using a Urinary Marker and a Mobile Cystoscopy Unit

Launched by JØRGEN BJERGGAARD JENSEN · Feb 26, 2024

Keywords

ClinConnect Summary

This study, called GreenBladder, is an observational research project that aims to find out whether a urine test called the Xpert Bladder Cancer Detection Test can help doctors decide who really needs a cystoscopy (a procedure that looks inside the bladder). The idea is to use this urine test to guide decisions, so some people might be able to avoid cystoscopy if the test suggests there’s no bladder cancer, which could speed up diagnosis for those with cancer and reduce unnecessary procedures, especially in Greenland where medical resources can be limited. The study will check how accurately the urine test identifies bladder cancer in people who are already being evaluated for potential bladder tumors.

Who can participate and what to expect: adults 18 years or older who live in Greenland and are on the waiting list to have a cystoscopy can join, as long as they can understand information in Danish or Greenlandic and give informed consent. Exclusion is simply not wanting to participate. Participants will provide a urine sample for the Xpert test during their planned cystoscopy appointment. The study will compare the test results with the cystoscopy findings to judge accuracy. The project is led by Aarhus University Hospital in Denmark, with participation from a hospital in Nuuk, Greenland, and collaborations with partner companies. It is currently enrolling by invitation, with an estimated 150 participants, and results could influence future bladder cancer screening and diagnosis strategies in Greenland and beyond.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • ≥18 years of age at the time of signing the Informed Consent Form with an indication for cystoscopy and planned for this already at study inclusion.
• • Ability to understand the Participant Information Sheet orally and in writing in either Danish or Greenlandic.
• • Signed Informed Consent Form.
• • Is, according to the Investigator's judgement, able to comply with the trial protocol.
• Exclusion Criteria:
• • Patients not willing to participate.