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Search / Trial NCT06282770

Photobiomodulation for Lower Back Pain Post Spinal Fusion and Decompression Surgery

Launched by UNIVERSITY OF CALIFORNIA, LOS ANGELES · Feb 26, 2024

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Photobiomodulation Laser Diode Inflammation Spinal Fusion Spinal Decompression Lumbar Back Pain

ClinConnect Summary

This clinical trial is investigating the use of a special laser treatment, called photobiomodulation, to help reduce pain and inflammation in patients who have had lower back surgery, specifically spinal fusion or decompression. After these surgeries, some patients may develop chronic lower back pain, and while there are existing treatments like medications and physical therapy, this study is looking at whether high-power laser lights can offer additional relief. Participants will be divided into two groups: one will use a back brace equipped with the laser treatment, while the other will use a standard brace that doesn’t provide the laser treatment, acting as a comparison.

To be eligible for this trial, you must be over 18 years old and have had lower back surgery within the last 1 to 5 years, experiencing pain for more than three months with a pain level of at least 4 out of 10. The study is currently recruiting participants, and it is open to all genders. Throughout the trial, participants will also have their surgical wounds monitored to see how well they are healing while using the brace. If you have certain medical conditions or a history of drug misuse, you may not be able to participate, but if you meet the criteria, this trial could be a chance to explore a new treatment for your back pain.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Subject will have undergone minimally invasive spinal fusion surgery or spinal decompression surgery in their lower back L1-S1.
  • Have low back pain of \>3 months and a pain threshold of \> 4 (as described by the the subject), age \> 18 years, and English speaking to eliminate possible miscommunication and consequent human error regarding belt use.
  • Subject must have had surgery at minimum to 1 year prior to start of study and no more than 5 years prior to start to study
  • Exclusion Criteria:
  • Patients with tumors
  • Current infection
  • Drug misuse history
  • Skin conditions preclude the use of laser belt
  • Severe spondylolisthesis, spondylolysis, spinal stenosis, ankylosing spondylitis
  • Previous low back surgery exceeding 5 years to initial start date.

About University Of California, Los Angeles

The University of California, Los Angeles (UCLA) is a prestigious academic institution renowned for its commitment to research and innovation in the biomedical field. As a clinical trial sponsor, UCLA leverages its cutting-edge facilities, expert faculty, and collaborative environment to advance medical knowledge and improve patient care. The university is dedicated to conducting rigorous clinical research that adheres to the highest ethical standards, aiming to translate scientific discoveries into effective therapies and interventions. Through its diverse array of clinical trials, UCLA seeks to address critical health challenges while fostering the development of future healthcare leaders.

Locations

Los Angeles, California, United States

Los Angeles, California, United States

Patients applied

0 patients applied

Trial Officials

Sara K Chung, PA

Study Director

University of California, Los Angeles

Sandra M Holley, PhD

Study Director

University of California, Los Angeles

Sichen Li, PhD

Study Director

University of California, Los Angeles

Adreanne Rivera, BS

Study Director

University of California, Los Angeles

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported