METabolomic and Immune PROfiling in the Development of Pancreatic Fistulas After cepHalic duodEnopancreatectomy

Launched by CENTRE HOSPITALIER UNIVERSITAIRE DE BESANCON · Feb 22, 2024

Keywords

ClinConnect Summary

This clinical trial is exploring ways to predict and prevent complications that can occur after a specific type of surgery called pancreaticoduodenectomy, which is performed on patients with pancreatic conditions. The main focus is to identify certain biological markers and immune responses in patients that may indicate their risk of developing issues like pancreatic fistulas (leaks from the pancreas) or acute pancreatitis (inflammation of the pancreas) after the surgery. By examining samples of pancreatic tissue and blood before and after surgery, researchers hope to gather valuable information to improve patient outcomes.

To participate in this study, you must be an adult scheduled for elective pancreaticoduodenectomy and agree to take part in the research. If you qualify, you can expect the usual surgical care, along with some additional tests involving tissue and blood samples to help with the study. It's important to note that this trial is not for patients requiring emergency surgery, pregnant individuals, or those unable to provide consent. By joining this study, you could help advance our understanding of how to better prevent complications following this type of surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • patients scheduled to undergo elective pancreaticoduodenectomy
• • Non-opposition of the subject to participate in the study.
• • Affiliated to the French social security system (CMU included).
• Exclusion Criteria:
• • Emergent surgery.
• • Pregnant patients.
• • Refusal to participate or inability to provide informed consent.
• • Patient under legal protection (individuals under guardianship by court order).