Application of FAPI and FDG PET Imaging in Patients With Different Types of Cancer

Launched by DAPING HOSPITAL AND THE RESEARCH INSTITUTE OF SURGERY OF THE THIRD MILITARY MEDICAL UNIVERSITY · Feb 21, 2024

Keywords

ClinConnect Summary

This clinical trial is investigating two types of imaging tests, called FAPI and FDG PET scans, to see how well they can help doctors find different types of cancer. Both types of imaging use special substances that highlight cancer cells, but they work in slightly different ways. The goal is to find out if the new FAPI imaging might be better at spotting tumors than the traditional FDG imaging, especially since it targets specific cancer-related cells that are usually not present in healthy tissues.

To participate in this trial, people must be at least 18 years old and have a suspected or newly diagnosed cancer. They should also be able to undergo both types of scans within one week and provide consent for participation. Unfortunately, pregnant women and those with certain health conditions that affect their ability to have the scans may not be eligible. Participants can expect to have both imaging tests done to help researchers learn more about how these methods compare in detecting cancer. This study is important because it may lead to better ways to diagnose and treat cancer in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Adult patients (≥ 18 years old);
• • 2. Suspected or newly diagnosed malignant tumor patients;
• • 3. Patients who underwent 18F-FDG and 18F-FAPI PET scans within one week;
• • 4. Patients who are able to provide informed consent forms (signed by participants, parents, or legal representatives) and consent forms in accordance with the guidelines of the Clinical Research Ethics Committee.
• Exclusion Criteria:
• • 1. Pregnant women;
• • 2. Scanned images with poor image quality due to factors such as body movement;
• • 3. Patients with mental illness or other unsuitable conditions for examination, poor compliance, etc.