Effectiveness of Povidone-Iodine Versus Chlorhexidine Gluconate Solutions in Reducing Microbial Contamination in Spinal Surgery Wounds During Intraoperative Soaking.

Launched by NATIONAL CHENG-KUNG UNIVERSITY HOSPITAL · Feb 21, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how well two different antiseptic solutions—povidone-iodine and chlorhexidine gluconate—work to reduce bacteria in wounds during spine surgery. The goal is to find out which solution is more effective in keeping surgical wounds clean and preventing infections. Additionally, the researchers will look into any side effects that might come from using these solutions during the surgery.

To participate in this study, patients need to be diagnosed with a condition called lumbar spinal stenosis, which means they have narrowing of the spinal canal that may require surgery. Specifically, they should be scheduled for a type of surgery called posterior lumbar decompression with fusion. However, individuals who have allergies to these disinfectants, who have had previous surgeries at the same site, or who currently have an active infection will not be eligible. Participants can expect to receive either povidone-iodine or chlorhexidine during their surgery, and the researchers will monitor them for any side effects as well as how well their wounds heal.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients who were diagnosed with lumbar spinal stenosis need to undergo posterior lumbar decompression with fusion surgery.
• Exclusion Criteria:
• • People who are allergic to disinfectants (Providine or CHG)
• • The surgical site has been operated before.
• • Patients under active infection status.