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Search / Trial NCT06284473

Ketamine as a Supplement to Local Anesthesia for Minor Procedures

Launched by LOYOLA UNIVERSITY · Feb 22, 2024

Trial Information

Current as of July 24, 2025

Recruiting

Keywords

In Ketamine Sub Dissociative Dose Minor Procedure

ClinConnect Summary

This clinical trial is studying whether adding ketamine, a medication known for its pain-relieving properties, can help reduce pain during minor procedures in the Emergency Department (ED). Participants, including both adults and children aged 7 to under 70, will be divided into two groups. One group will receive ketamine along with standard local anesthesia, while the other group will receive a saline solution (a harmless saltwater solution) along with the same local anesthesia. The main goal is to see if those receiving ketamine report less pain compared to those receiving saline.

To be eligible for this trial, participants must be undergoing a minor procedure in the ED and weigh no more than 115 kg (about 253 pounds). However, certain individuals are excluded, such as those with altered mental status, pregnant or breastfeeding women, and those with specific medical conditions like a history of seizures or psychiatric illness. Participants can expect to provide feedback on their pain levels and, for adults, their level of agitation or alertness. This trial aims to find safer and more effective ways to manage pain during minor procedures, which could lead to more research in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Undergoing Minor Procedure in the ED
  • Weight not to exceed 115kg
  • Exclusion Criteria:
  • Altered Mental Status
  • Pregnancy
  • Breastfeeding
  • Acute head or eye injury
  • Intercranial Hypertension
  • Hx of seizures
  • Hx of chronic pain
  • Unstable vital signs
  • Allergy to Ketamine
  • Hepatic or Renal Insufficiency
  • Hx of Psychiatric Illness
  • Hx of alcohol/drug abuse

About Loyola University

Loyola University is a prestigious academic institution dedicated to advancing medical research and clinical innovation. As a sponsor of clinical trials, Loyola University leverages its extensive resources, expert faculty, and commitment to ethical research practices to explore new therapeutic interventions and improve patient outcomes. The university fosters a collaborative environment that brings together multidisciplinary teams to conduct rigorous studies across various fields of medicine, ensuring that the findings contribute to the broader healthcare community and enhance evidence-based practices. Through its dedication to scientific excellence and community health, Loyola University remains at the forefront of clinical research initiatives.

Locations

Maywood, Illinois, United States

Patients applied

0 patients applied

Trial Officials

Trent Reed, DO

Principal Investigator

Loyola University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported