Ketamine as a Supplement to Local Anesthesia for Minor Procedures

Launched by LOYOLA UNIVERSITY · Feb 22, 2024

Keywords

ClinConnect Summary

This clinical trial is studying whether adding ketamine, a medication known for its pain-relieving properties, can help reduce pain during minor procedures in the Emergency Department (ED). Participants, including both adults and children aged 7 to under 70, will be divided into two groups. One group will receive ketamine along with standard local anesthesia, while the other group will receive a saline solution (a harmless saltwater solution) along with the same local anesthesia. The main goal is to see if those receiving ketamine report less pain compared to those receiving saline.

To be eligible for this trial, participants must be undergoing a minor procedure in the ED and weigh no more than 115 kg (about 253 pounds). However, certain individuals are excluded, such as those with altered mental status, pregnant or breastfeeding women, and those with specific medical conditions like a history of seizures or psychiatric illness. Participants can expect to provide feedback on their pain levels and, for adults, their level of agitation or alertness. This trial aims to find safer and more effective ways to manage pain during minor procedures, which could lead to more research in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Undergoing Minor Procedure in the ED
• • Weight not to exceed 115kg
• Exclusion Criteria:
• • Altered Mental Status
• • Pregnancy
• • Breastfeeding
• • Acute head or eye injury
• • Intercranial Hypertension
• • Hx of seizures
• • Hx of chronic pain
• • Unstable vital signs
• • Allergy to Ketamine
• • Hepatic or Renal Insufficiency
• • Hx of Psychiatric Illness
• • Hx of alcohol/drug abuse