the Impact of Manual or Mechanical Ways to Perform PLR on the Accuracy of Evaluation of Fluid Responsiveness

Launched by SOUTHEAST UNIVERSITY, CHINA · Feb 28, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how different methods of a procedure called passive leg raising (PLR) can help doctors better understand if patients with circulatory failure need more fluids. PLR involves raising a patient's legs to see how their body reacts, which can indicate whether they are responding well to fluids. The trial aims to find out if doing this manually (by hand) or mechanically (using a device) makes a difference in the accuracy of these evaluations.

To participate in the study, patients need to be between 65 and 75 years old and show signs of poor blood flow, such as increased lactate levels or low blood pressure. They must be in an intensive care unit and have a specific type of heart monitoring in place. However, those under 18 or over 75, pregnant women, or individuals unable to safely undergo PLR will not be eligible. If you choose to take part, the study will help researchers learn more about how to assess fluid needs in critically ill patients, ultimately aiming to improve care for those in similar situations.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • (1) patients who have signs of tissue hypo-perfusion (increasing lactate levels, in need of vasopressor agents to maintain blood pressure, oliguria, and weak consciousness), and need to evaluate their fluid responsiveness; (2) patients who have received Pulse indicator Continuous Cardiac Output (PiCCO) monitoring ; (3) patients who are transferred into the intensive care department.
• Exclusion Criteria:
• • (1) Age \< 18 years old, or \> 75 years old (2) pregnancy or lactation; (3) refusal to sign the informed consent form for enrollment; (4) patients who are clearly unable to perform passive leg raising (PLR) (intra-abdominal pressure ≥16cmH2O, high risk of lower limb venous thrombosis, intracranial hypertension, and recent undergone abdominal or pelvic surgery); (5) patients with the contraindications of fluid resuscitation therapy ( pulmonary edema, intracranial hypertension and so on); (6) patients clinical doctors assessed as unsuitable for PLR.