Clinical Characteristics of Small Intestinal Bacterial Overgrowth in Individuals with Abdominal Distention

Launched by SHANDONG UNIVERSITY · Feb 28, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a condition called abdominal distention, which is when a person's stomach feels swollen or bloated. Researchers want to understand how often this feeling is linked to a specific problem called small intestinal bacterial overgrowth (SIBO) and how food moves through the digestive system. They will use a simple breath test, which is non-invasive, to check for SIBO and other issues related to how food travels in the intestines. The goal is to gain insights that could help doctors better diagnose and treat people experiencing abdominal distention.

To participate in this study, individuals need to be between 18 and 70 years old and mainly complain about bloating or a swollen abdomen. However, some people may not be eligible, such as those who are pregnant, have had recent surgeries, or take certain medications. If someone decides to join the trial, they can expect to undergo the breath test and contribute to important research that may improve understanding of abdominal issues.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients aged 18 to 70 years.
• • 2. Patients presenting with the primary complaint of abdominal bloating and/or abdominal distension, or those exhibiting abdominal distension with prominence over other symptoms.
• Exclusion Criteria:
• • 1. Patients who are pregnant or lactating.
• • 2. Patients have history of gastrointestinal malignancy or gastrointestinal surgery.
• • 3. Patients manifesting food intolerance or presenting with a confirmed diagnosis or suspicion of lactose intolerance.
• • 4. Patients with urinary system (chronic kidney disease, etc.), immune system (scleroderma, etc.), nervous system (Parkinson's disease, etc.), mental system (depression, etc.), or other diseases outside the digestive system.
• • 5. Patients who used antibiotics or microecological agents or underwent endoscopic examination within two weeks.
• • 6. Patients with a medication history encompassing motility enhancers, secretory enhancers, antifoaming agents, spasmolytics, opioids, and antidepressants within the past week.
• • 7. Patients who are unwilling or incapable to provide informed consents.