Aortopathy Relationship to Imagery and Kinocardiography Features (ARTIK)

Launched by UNIVERSITÉ LIBRE DE BRUXELLES · Feb 22, 2024

Keywords

ClinConnect Summary

The ARTIK trial is studying a new technique called kinocardiography (KCG) to better understand how the heart works in patients with aortic valve disease (AVD) and thoracic aortic aneurysm (TAA). The goal is to see if KCG can help doctors diagnose these heart conditions more effectively. Participants in the study will have their heart function assessed using KCG, along with other imaging techniques like echocardiography and cardiac MRI, to compare those with AVD or TAA to healthy individuals.

To join the study, participants need to be adults over 18 years old. Those who have severe AVD or TAA and are being considered for interventional treatment can join one group, while others with varying degrees of AVD can join another group. There is also a control group for healthy participants matched by age and gender. It’s important to note that individuals with serious heart rhythm problems or those unable to provide consent will not be eligible. Participants can expect to undergo various tests to help researchers learn more about the relationship between KCG and these heart conditions.

Gender

ALL

Eligibility criteria

• • Inclusion Criteria
• • "Interventional treatment" group
• • Adults (\>18 y)
• • Interventional treatment indication for severe AVD and/or severe TAA, as decided by the Heart Team
• • "Aortic valve disease of different severities" group
• • Adults (\>18y)
• • Aortic stenosis and/or aortic regurgitation and/or bicuspidy of different severities confirmed by echocardiography and/or cardiac MRI
• • "Control" group : - Adults (\>18 y) appariated with the participants of other groups according to their age, sex, body surface area and LVEF
• Exclusion Criteria:
• • Any severe rhythm disorder such as frequent ventricular extrasystoles, atrial tachyarrhythmias
• • Subject's disabilty to give consent
• • Subjects suffering from aortic valve disease or thoracic aortic aneurysm will be excluded from the "control" group.