An Investigation Into Taste Problems Associated With Xerostomia in Patients With Advanced Cancer

Launched by OUR LADY'S HOSPICE AND CARE SERVICES · Feb 22, 2024

Keywords

ClinConnect Summary

This clinical trial is looking into how dry mouth (xerostomia) affects taste in patients with advanced cancer. Many people with cancer experience taste problems and dry mouth, which can make eating and drinking less enjoyable, lead to eating less, and even impact their mood and overall quality of life. The study aims to understand the link between these two issues to help improve care for patients undergoing treatment.

To be eligible for this trial, participants must be at least 18 years old and have a diagnosis of advanced cancer. They should be experiencing moderate or more severe dry mouth and taste problems in the last two weeks. Participants need to be able to understand English well. However, those with certain conditions, such as cognitive impairment or previous head and neck surgeries, cannot join. If eligible, participants can expect to share their experiences through questionnaires and discussions that will help researchers learn more about these symptoms and how they affect daily life.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 18 years of age
• • Diagnosis of locally advanced or metastatic cancer
• • Referred to palliative care/oncology services
• • Dry mouth rated 'moderate' or worse over previous 2-week period
• • Taste problems rated 'moderate' or worse over previous 2-week period
• • Good understanding of English
• Exclusion Criteria:
• • Cognitive impairment (unable to provide consent / complete questionnaire)
• • Dry mouth precedes cancer diagnosis.
• • Taste problems precedes cancer diagnosis.
• • Head and neck surgery
• • Head and neck radiotherapy
• • Salivary gland disorders (e.g., Sjogren's Syndrome)
• • In the 'Deteriorating' or 'Terminal' Phase of illness