MOdifiable facTors to Improve VentilAtion ThErapy in ICU

Launched by NAT INTENSIVE CARE SURVEILLANCE - MORU · Feb 24, 2024

Keywords

ClinConnect Summary

The MOdifiable facTors to Improve VentilAtion ThErapy in ICU trial is researching ways to improve the care of patients who need invasive mechanical ventilation (a type of breathing support) in intensive care units (ICUs) in Uganda. The goal is to find specific factors that could help reduce the number of patients who do not survive their ICU stay. This study will look at both patient-related factors (like age and health conditions) and factors related to how care is provided in the ICU (such as staff levels and sedation practices). By understanding these factors, the researchers hope to improve outcomes for critically ill patients in low and middle-income countries.

To participate in this study, patients who are 15 years or older and require invasive mechanical ventilation during their hospital stay may be eligible. Those who have been successfully taken off the ventilator within two days, are receiving end-of-life care, or are transferred from non-participating ICUs will not be included. Participants will be monitored for their ICU stay, how long they need ventilation, and any complications that arise. Importantly, patient privacy will be protected throughout the study, and the findings will be shared to help improve care in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Invasive mechanical ventilatory support initiated anywhere within the study hospital i.e., emergency room, normal ward or in the operating room, or in the ICU at any time during admission.
• Exclusion Criteria:
• • Successful extubations within two calendar days of intubation
• • Admissions for end-of-life care and/or ICU palliative support
• • Patients transferred from ICUs not participating in the study 24 hours after initiation of MV.
• • Refusal or Withdrawal of consent