Protective Effect of Indocyanine Green Fluorescence Imaging Technology on Parathyroid Glands During Total Thyroidectomy

Launched by SHANDONG LINGLONG YINGCHENG HOSPITAL · Feb 25, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at a new way to help protect the parathyroid glands during a surgery called total thyroidectomy, which is the removal of the thyroid gland. The researchers want to find out if using a special imaging technique, called indocyanine green fluorescence imaging, along with another method called autofluorescence, can help doctors better see and evaluate the parathyroid glands during surgery. This approach aims to reduce the risk of a condition called hypoparathyroidism, which can occur after surgery and affects calcium levels in the body.

To participate in this trial, you need to be an adult aged 18 or older who is scheduled for thyroid surgery. You should have normal liver and kidney function and not have any allergies to indocyanine green or iodine. If you join the study, you can expect to undergo the standard procedures for thyroid surgery, with additional imaging techniques to help protect your parathyroid glands. The study is currently recruiting participants, and it’s important that you understand the study process and are willing to give your consent to participate.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Male or female patients, aged 18 years and above
• • Scheduled for elective total or hemi thyroidectomy
• • Normal liver and renal function
• • No known hypersensitivity for iodine or ICG
• • Able to understand the nature of the study procedures
• • Willing to participate and give written informed consent
• Exclusion Criteria:
• • Age \< 18 years
• • Liver or renal insufficiency
• • Known ICG, iodine, penicillin or sulfa hypersensitivity
• • Pregnancy or breastfeeding
• • Not able to understand the nature of the study procedure
• • Not willing to participate