Autonomic Dysfunction in Patients Following Bariatric Surgery: The ADiPOSE Study

Launched by KANSAS CITY HEART RHYTHM RESEARCH FOUNDATION · Feb 26, 2024

Keywords

ClinConnect Summary

The ADiPOSE Study is a clinical trial that looks at how common autonomic dysfunction (AD) is in people who have had bariatric surgery, such as gastric bypass or sleeve gastrectomy. Autonomic dysfunction can cause symptoms like feeling dizzy when standing up, known as orthostatic intolerance. The study aims to understand how this condition affects patients after their surgery and to learn more about the reasons behind it.

To participate, individuals must be between 18 and 85 years old, able to provide consent, and have undergone or are planning to undergo specific types of bariatric surgery. Participants will either have had the surgery within the last three years or will have it soon. The study is currently recruiting participants, and those who join can expect to share their experiences and health outcomes related to autonomic dysfunction with the research team. This information will help improve our understanding of how bariatric surgery impacts the nervous system and may lead to better care for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Between the age of 18 - 85 years
• • Can provide consent
• • Negative urine B-hCG
• • Continued follow-up with the bariatric surgery team.
• • BS includes one of the following: gastric bypass, sleeve gastrectomy, and biliopancreatic diversion with duodenal switch.
• • Phase I: Underwent BS within the last 3 years
• • Phase II: Will undergo BS within the next 3 months or underwent BS in the last 30 days
• Exclusion Criteria:
• • Unable to provide consent
• • Pregnant or breastfeeding
• • BMI \< 35
• • Revision surgery of one of the following BS from above
• • Prior history of autonomic dysfunction prior to BS
• • Developed AD 72 months post-procedure
• • No evidence of AD/OI