Vasopressin Versus Tranexamic Acid for Control of Blood Loss Related to Abdominal Hysterectomy

Launched by AL-AZHAR UNIVERSITY · Feb 27, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how well two different medications—vasopressin and tranexamic acid—work to reduce blood loss during abdominal hysterectomy surgery in women. An abdominal hysterectomy is a procedure to remove the uterus, often due to non-cancerous conditions. The researchers want to find out which of these medications is more effective at controlling blood loss during this type of surgery.

To participate in the trial, women who are scheduled for an abdominal hysterectomy for benign (non-cancerous) reasons may be eligible. However, individuals with bleeding disorders, those taking blood-thinning medications, or those with certain other health issues will not be included. If you join the study, you will receive either vasopressin or tranexamic acid during your surgery, and the team will monitor your blood loss to see which treatment works better. This research is important to help improve care for women undergoing this common surgery.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • - Patients will be included in the present study if they are indicated for abdominal hysterectomy for benign lesions.
• Exclusion Criteria:
• • history of coagulation or bleeding disorders or
• • if they were under antithrombotic treatment.
• • associated malignancy, renal impairment or allergy to TA.