Continuous Versus Intermittent Nebulization Therapy in Acute Asthma Exacerbation at Emergency Department

Launched by THAMMASAT UNIVERSITY · Feb 26, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how two different methods of delivering medication can help people with asthma who are having a severe attack while in the emergency department. The researchers want to find out if giving the medication continuously for an hour or in short bursts every 20 minutes is more effective in easing symptoms and reducing the time patients spend in the emergency department. The medications used in both methods include budesonide, fenoterol, ipratropium bromide, and normal saline. The trial will also look at how well patients breathe and how many might need to stay in the hospital after their visit.

To participate in this trial, you should be experiencing an asthma exacerbation, which means your asthma symptoms are getting worse. However, if you have certain serious conditions, like needing a breathing tube or allergies to the medications being used, you won’t be able to join. If you decide to participate, you’ll be randomly assigned to one of the two treatment groups and monitored carefully for your symptoms and overall well-being during and after the treatment. This trial is not yet recruiting participants, so you’ll need to wait for it to start.

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Eligibility criteria

• Inclusion Criteria:
• • asthma exacerbation
• Exclusion Criteria:
• • life-threatening conditions requiring intubation
• • allergy to steroid or its components
• • patient under investigation of Corona Virus Disease, 2019 (COVID-19)
• • pulmonary tuberculosis
• • unable to cooperate for pulmonary function testing