A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)
Launched by ELI LILLY AND COMPANY · Mar 1, 2024
Trial Information
Current as of May 04, 2025
Recruiting
Keywords
ClinConnect Summary
The ACCLAIM-Lp(a) trial is studying a new treatment called lepodisiran to see if it can help reduce the risk of serious heart problems in adults who have high levels of a substance called lipoprotein(a), which can increase the chance of heart attacks and strokes. This study is specifically looking at adults who either already have heart disease or are at risk of developing it. If you are between 18 and 74 years old and have high lipoprotein(a) levels, you might qualify to participate.
Participants in this study will receive the treatment through an injection under the skin. The trial is currently recruiting, and it’s important to note that certain health conditions may prevent someone from joining, such as recent major heart events or uncontrolled high blood pressure. If you decide to participate, you’ll have the opportunity to contribute to important research that could help others at risk for heart disease.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Have Lipoprotein(a) \[Lp(a)\] ≥175 nanomoles per liter (nmol/L).
- * Meet criteria of either 2a or 2b:
- • 2a: Individuals 18 years of age or older with established atherosclerotic cardiovascular disease (ASCVD) with an event or revascularization.
- • 2b: Individuals 55 years of age or older who are at risk for a first cardiovascular (CV) event and either: Documented coronary artery disease (CAD), carotid stenosis, or peripheral artery disease (PAD) without history of event or revascularization; known familial hypercholesteremia; or a combination of high-risk factors.
- Exclusion Criteria:
- • Have had a major cardiovascular event or surgery, such as myocardial infarction (MI), stroke or coronary or peripheral revascularization, \< 60 days before screening
- • Have uncontrolled hypertension
- • Have New York Heart Association class IV heart failure.
- • Have lipoprotein apheresis within 90 days of screening, or planned lipoprotein apheresis during the study.
- • Have severe renal failure, defined as
- • Estimated glomerular rate (eGFR) \<15 milliliters per minute per 1.73 meters squared (mL/min/1.73m2) at screening Visit 1, or ongoing dialysis.
- • Have a diagnosis of active nephrotic syndrome, or urine albumin-creatinine ratio (UACR) of ≥5000 mg/g at screening Visit 1.
- • Have acute or chronic hepatitis, known cirrhosis, signs and symptoms of any other liver disease other than metabolic-associated steatotic liver disease, or exclusionary laboratory results as determined by the central laboratory during screening.
About Eli Lilly And Company
Eli Lilly and Company is a global healthcare leader dedicated to creating innovative medicines that improve patient outcomes across a range of therapeutic areas, including diabetes, oncology, immunology, and neurodegenerative diseases. With a rich history of scientific research and a commitment to advancing healthcare, Lilly invests significantly in clinical trials to develop new treatments and enhance existing therapies. The company prioritizes patient safety and ethical standards in its clinical research, fostering collaboration with healthcare professionals and stakeholders to ensure the delivery of high-quality, evidence-based solutions that address unmet medical needs worldwide.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Brandýs Nad Labem Stará Boleslav, Praha Východ, Czechia
Ricany, Středočeský Kraj, Czechia
Uherské Hradiště, Zlínský Kraj, Czechia
Bad Homburg, Hessen, Germany
Leipzig, Sachsen, Germany
Bad Friedrichshall, , Germany
Ypsilanti, Michigan, United States
Lanus, Buenos Aires, Argentina
Rosario, Santa Fe, Argentina
Hefei, Anhui, China
Sosa Gu, Kyǒnggi Do, Korea, Republic Of
Seoul, Seoul Teukbyeolsi [Seoul], Korea, Republic Of
Daegu, Taegu Kwangyǒkshi, Korea, Republic Of
Mexico City, Distrito Federal, Mexico
Daegu, Taegu Kwangyǒkshi, Korea, Republic Of
Mexico, Distrito Federal, Mexico
Mexico City, Distrito Federal, Mexico
Tlalpan, Distrito Federal, Mexico
León, Guanajuato, Mexico
Bydgoszcz, Kujawsko Pomorskie, Poland
Grudziadz, Kujawsko Pomorskie, Poland
Rimavská Sobota, Banskobystrický Kraj, Slovakia
Krakow, Małopolskie, Poland
Tarnow, Małopolskie, Poland
Malacky, Bratislavský Kraj, Slovakia
Lubochna, žilinský Kraj, Slovakia
Taichung City, Taichung, Taiwan
Nitra, Nitriansky Kraj, Slovakia
Presov, Prešovský Kraj, Slovakia
Salford, Manchester, United Kingdom
Glasgow, Scotland, United Kingdom
Tyne And Wear, , United Kingdom
New Taipei, , Taiwan
Kanwal, New South Wales, Australia
Guadalajara, Jalisco, Mexico
London, England, United Kingdom
Martin, žilinský Kraj, Slovakia
Piešťany, Trnavský Kraj, Slovakia
Sunto Gun, Shizuoka, Japan
Seongnam, Kyǒnggi Do, Korea, Republic Of
Wuhu, Anhui, China
Kosice, Košický Kraj, Slovakia
Remscheid, Nordrhein Westfalen, Germany
Stevenage, Hertfordshire, United Kingdom
Warsaw, Mazowieckie, Poland
Austin, Texas, United States
Warsaw, Mazowieckie, Poland
Brasília, Distrito Federal, Brazil
Maceio, Alagoas, Brazil
Salvador, Bahia, Brazil
Brasília, Distrito Federal, Brazil
Bequimao, Maranhão, Brazil
Dresden, Sachsen, Germany
Vitória, Espírito Santo, Brazil
Dresden, Sachsen, Germany
Kedzierzyn Kozle, Opolskie, Poland
Bielsko Biala, śląskie, Poland
Dolny Kubin, žilinský Kraj, Slovakia
Caba, Buenos Aires, Argentina
San Martín, Buenos Aires, Argentina
Rochdale, Manchester, United Kingdom
Lancaster, Pennsylvania, United States
Seoul, , Korea, Republic Of
Chrzanow, Małopolskie, Poland
Berlin, , Germany
Dolny Kubin, žilinský Kraj, Slovakia
Peoria, Arizona, United States
Phoenix, Arizona, United States
Chongqing, Chongqing, China
West Bromwich, , United Kingdom
Kenosha, Wisconsin, United States
Trstena, žilinský Kraj, Slovakia
Kolin, Středočeský Kraj, Czechia
Suwon Si, Kyǒnggi Do, Korea, Republic Of
Lugo, , Spain
Rožňava, Košický Kraj, Slovakia
Changhua County, Changhua, Taiwan
Shanghai, Shanghai, China
Berlin, , Germany
Torrance, California, United States
Aurora, Colorado, United States
Palm Springs, California, United States
Hartford, Connecticut, United States
Simi Valley, California, United States
Macon, Georgia, United States
Miami, Florida, United States
Atlanta, Georgia, United States
Bossier City, Louisiana, United States
New York, New York, United States
Hyattsville, Maryland, United States
Saratoga Springs, New York, United States
Cleveland, Ohio, United States
Stony Brook, New York, United States
Columbus, Ohio, United States
San Antonio, Texas, United States
Camp Hill, Pennsylvania, United States
Philadelphia, Pennsylvania, United States
Shavano Park, Texas, United States
Sherman, Texas, United States
Liverpool, New South Wales, Australia
Mistelbach, Niederösterreich, Austria
Braunau, Oberösterreich, Austria
Morgantown, West Virginia, United States
Ciudad Autónoma De Buenos Aires, Buenos Aires, Argentina
Edegem, Antwerpen, Belgium
Buenos Aires, Ciudad Autónoma De Buenos Aires, Argentina
Brasilia, Distrito Federal, Brazil
Los Angeles, California, United States
Oostende, West Vlaanderen, Belgium
Las Vegas, Nevada, United States
New York, New York, United States
Atlanta, Georgia, United States
New York, New York, United States
Murray, Utah, United States
São Paulo, , Brazil
Meadowbrook, Queensland, Australia
Pittsburgh, Pennsylvania, United States
Innsbruck, Tirol, Austria
Beijing, Beijing, China
Rapid City, South Dakota, United States
Beijing, Beijing, China
Sao Paulo, São Paulo, Brazil
Gent, Oost Vlaanderen, Belgium
Salvador, Bahia, Brazil
Brasilia, Distrito Federal, Brazil
São José Do Rio Preto, São Paulo, Brazil
Guangzhou, Guangdong, China
Guangzhou, Guangdong, China
Nanjing, Jiangsu, China
Changsha, Hunan, China
Nanjing, Jiangsu, China
Yueyang, Hunan, China
Nanchang, Jiangxi, China
Shenyang, Liaoning, China
Changchun, Jilin, China
Changchun, Jilin, China
Siping, Jilin, China
Jinan, Shandong, China
Xi'an, Shaanxi, China
Xian, Shaanxi, China
Brno, Brno Město, Czechia
Cheng Du, Sichuan, China
Tianjin, Tianjin, China
Herlev, Hovedstaden, Denmark
Nice, Alpes Maritimes, France
Hangzhou, Zhejiang, China
Strasbourg, Alsace, France
Marseille, Bouches Du Rhône, France
Toulouse, Haute Garonne, France
Compiègne, Oise, France
Paris, Orne, France
Besançon, Doubs, France
Le Coudray, Eure Et Loir, France
Pau, Pyrénées Atlantiques, France
Bron, Rhône, France
Mannheim, Baden Württemberg, Germany
Köln, Nordrhein Westfalen, Germany
Paris, , France
Magdeburg, Sachsen Anhalt, Germany
Paleo Faliro, Attikí (Region), Greece
Athens, Attikí, Greece
Chaidari, Attikí, Greece
Dresden, Sachsen, Germany
Thessaloniki, Kentrikí Makedonía, Greece
Belagavi, Karnataka, India
Budapest, , Hungary
Budapest, , Hungary
Nashik, Maharashtra, India
Budapest, , Hungary
Haifa, Hatsafon, Israel
Kfar Saba, Hamerkaz, Israel
Nahariya, Hatsafon, Israel
Petah Tikva, Hamerkaz, Israel
Tel Aviv, Tell Abīb, Israel
Haifa, ḥeifā, Israel
Milan, Milano, Italy
Ferrara, Emilia Romagna, Italy
Rome, Lazio, Italy
Genova, Liguria, Italy
Yokosuka, Kanagawa, Japan
Pisa, Toscana, Italy
Arzignano, Veneto, Italy
Padova, Veneto, Italy
Gwangju Si, Kwangju Kwangyǒkshi, Korea, Republic Of
Bucheon Si, Kyǒnggi Do, Korea, Republic Of
Miyakonojo, Miyazaki, Japan
Mexico City, Distrito Federal, Mexico
Seoul, Seoul Teukbyeolsi [Seoul], Korea, Republic Of
Seoul, Seoul Teukbyeolsi [Seoul], Korea, Republic Of
Xalapa, Veracruz, Mexico
Gouda, Zuid Holland, Mexico
Utrecht, , Mexico
San Nicolas De Los Garza, Nuevo León, Mexico
Amersfoort, Utrecht, Mexico
Doetinchem, Gelderland, Netherlands
Leeuwarden, Fryslân, Netherlands
Den Bosch, Noord Brabant, Netherlands
Eindhoven, Noord Brabant, Netherlands
Roosendaal, Noord Brabant, Netherlands
Amsterdam, Noord Holland, Netherlands
Amsterdam, Noord Holland, Netherlands
Hilversum, Noord Holland, Netherlands
Zaandam, Noord Holland, Netherlands
Beverwijk, Noord Holland, Netherlands
Deventer, Overijssel, Netherlands
Goes, Zeeland, Netherlands
Leiden, Zuid Holland, Netherlands
Delft, Zuid Holland, Netherlands
Den Haag, Zuid Holland, Netherlands
Wrocław, Dolnośląskie, Poland
Gdańsk, Pomorskie, Poland
Krakow, Małopolskie, Poland
Craiova, Dolj, Romania
Bucharest, București, Romania
Baia Mare, Maramureș, Romania
Târgu Mureș, Mureș, Romania
Iași, , Romania
Timisoara, Timiș, Romania
A Coruña, A Coruña [La Coruña], Spain
Malaga, Andalucía, Spain
Gijón, Asturias, Spain
Barcelona, Barcelona [Barcelona], Spain
L'hospitalet De Llobregat, Catalunya [Cataluña], Spain
Sant Joan Despí, Catalunya [Cataluña], Spain
Cordoba, Andalucía, Spain
Granada, Andalucía, Spain
Las Palmas De Gran Canaria, Las Palmas, Spain
Alcorcón, Madrid, Comunidad De, Spain
Majadahonda, Madrid, Comunidad De, Spain
Sanlúcar De Barrameda, Cádiz, Spain
Seville, Sevilla, Spain
Madrid, , Spain
Madrid, , Spain
Segovia, , Spain
Sevilla, , Spain
Stanford, California, United States
Baltimore, Maryland, United States
Saint Peters, Missouri, United States
Westlake Village, California, United States
Houston, Texas, United States
Clayton, Victoria, Australia
Leuven, Vlaams Brabant, Belgium
Vienna, Wien, Austria
Kortrijk, West Vlaanderen, Belgium
Goiania, Goiás, Brazil
Dijon, Bourgogne, France
Rennes, Bretagne, France
Mannheim, Baden Württemberg, Germany
Harbin, Heilongjiang, China
Zhengzhou, Henan, China
Chifeng, Inner Mongolia, China
Heraklion, Irakleío, Greece
Thessaloniki, Thessaloníki, Greece
Regensburg, Bayern, Germany
Szeged, Csongrád, Hungary
Lublin, Lubelskie, Poland
Jerusalem, Yerushalayim, Israel
Warsaw, Mazowieckie, Poland
Bucharest, București, Romania
Baia Mare, Maramureș, Romania
Madrid, Madrid, Comunidad De, Spain
Pozuelo De Alarcón, Madrid, Spain
Milan, Milano, Italy
Baggiovara, Modena, Italy
Reus, Tarragona [Tarragona], Spain
Bristol, Bristol, City Of, United Kingdom
Torquay, Devon, United Kingdom
Valencia, Valenciana, Comunitat, Spain
Salamanca, , Spain
Lyon, Rhône Alpes, France
Mesquite, Texas, United States
Târgu Mureș, Mureș, Romania
Wichita, Kansas, United States
Rouen, Haute Normandie, France
Baltimore, Maryland, United States
Porto Alegre, Rio Grande Do Sul, Brazil
Palma, Balears [Baleares], Spain
Warszawa, Mazowieckie, Poland
Bikaner, Rajasthan, India
Wien, , Austria
Wien, , Austria
Nanjing, Jiangsu, China
Aachen, Nordrhein Westfalen, Germany
Antwerp, Antwerpen, Belgium
Namdong Gu, Incheon Gwangyeoksi [Incheon], Korea, Republic Of
Charleroi, Hainaut, Belgium
Timișoara, Timiș, Romania
Alexandria, Louisiana, United States
Sao Paulo, São Paulo, Brazil
Vancouver, British Columbia, Canada
Ferrol, A Coruña [La Coruña], Spain
Beijing, Beijing, China
Brno, Brno Město, Czechia
Athens, Attikí, Greece
Ostrava, Ostrava Město, Czechia
Nyiregyhaza, Nyíregyháza, Hungary
Lucknow, Uttar Pradesh, India
Pessac, Aquitaine, France
Harderwijk, Gelderland, Netherlands
Przemysl, Podkarpackie, Poland
Seoul, Seoul Teukbyeolsi [Seoul], Korea, Republic Of
Mexico City, Distrito Federal, Mexico
Barcelona, Catalunya [Cataluña], Spain
Bucharest, București, Romania
Badalona, Barcelona [Barcelona], Spain
Valencia, Valenciana, Comunitat, Spain
Valencia, València, Spain
Wien, , Austria
Ioannina, Ioánnina, Greece
Debrecen, , Hungary
Indianapolis, Indiana, United States
Raipur, Chhattisgarh, India
Sibiu, , Romania
Bratislava, Bratislavský Kraj, Slovakia
Rotterdam, Zuid Holland, Netherlands
Santiago De Compostela, A Coruña [La Coruña], Spain
Falls Church, Virginia, United States
Matsumoto, Nagano, Japan
Lille, Nord, France
Rio De Janeiro, , Brazil
Bielefeld, Nordrhein Westfalen, Germany
Harbin, Heilongjiang, China
Leipzig, Sachsen, Germany
Balatongyorok, Veszprém, Hungary
Olomouc, , Czechia
Be'er Sheva, Hadarom, Israel
Hellerup, , Denmark
Rehovot, Hamerkaz, Israel
Holon, Hamerkaz, Israel
Pisa, Toscana, Italy
Ciudad De México, Distrito Federal, Mexico
Guadalajara, Jalisco, Mexico
Apeldoorn, Gelderland, Netherlands
Bologna, , Italy
Nijmegen, Gelderland, Netherlands
Milano, , Italy
Perugia, , Italy
Veldhoven, Noord Brabant, Netherlands
Haarlem, Noord Holland, Netherlands
Girona, Girona [Gerona], Spain
El Palmar, Murcia, Murcia, Región De, Spain
Brasschaat, Antwerpen, Belgium
Galați, , Romania
Galați, , Romania
Iași, , Romania
Dongjak Gu, Seoul Teukbyeolsi [Seoul], Korea, Republic Of
Paris, île De France, France
Wonju, Kang Won Do, Korea, Republic Of
Villamartin, Cádiz, Spain
Jaén, , Spain
Hull, Kingston Upon Hull, United Kingdom
Seoul, , Korea, Republic Of
Venlo, Limburg, Netherlands
Presov, Prešovský Kraj, Slovakia
Beltsville, Maryland, United States
Bonheiden, Antwerpen, Belgium
Paris, île De France, France
Hasselt, Limburg, Belgium
Jena, Thüringen, Germany
Berlin, , Germany
Nanning, Guangxi, China
Brno, Brno Město, Czechia
Bobigny, île De France, France
Athens, Attikí, Greece
Madrid, , Spain
Ede, Gelderland, Netherlands
Adelaide, South Australia, Australia
San Juan, , Puerto Rico
Bucharest, București, Romania
Brasov, , Romania
Dénia, Alicante, Spain
Ramat Gan, Hamerkaz, Israel
Mechelen, Antwerpen, Belgium
łódź, łódzkie, Poland
Huelva, , Spain
Belo Horizonte, Minas Gerais, Brazil
Brussels, Bruxelles Capitale, Région De, Belgium
Petah Tikva, Hamerkaz, Israel
Guadalajara, Jalisco, Mexico
Zaragoza, , Spain
Rotterdam, Zuid Holland, Netherlands
Satu Mare, , Romania
Porto Alegre, Rio Grande Do Sul, Brazil
Montpellier, Hérault, France
Santander, Cantabria, Spain
Barcelona, Catalunya [Cataluña], Spain
Porto Alegre, Rio Grande Do Sul, Brazil
Nantes Cedex 1, Loire Atlantique, France
Chambray Les Tours, Centre, France
Xiamen, Fujian, China
Allentown, Pennsylvania, United States
Jerusalem, Yerushalayim, Israel
Tilburg, Noord Brabant, Netherlands
St. Polten, Niederösterreich, Austria
Linz, Oberösterreich, Austria
Clearwater, Florida, United States
Brussels, Bruxelles Capitale, Région De, Belgium
Gilly, Hainaut, Belgium
Genk, Limburg, Belgium
Greenville, North Carolina, United States
Dendermonde, Oost Vlaanderen, Belgium
Corvallis, Oregon, United States
Hefei, Anhui, China
Recife, Pernambuco, Brazil
Washington, District Of Columbia, United States
Río Cuarto, Córdoba, Argentina
Nîmes, Gard, France
Nanyang, Henan, China
Firenze, Toscana, Italy
Jingzhou, Hubei, China
Wuhan, Hubei, China
Berlin, , Germany
São Paulo, , Brazil
Zalaegerszeg, Zala, Hungary
Vejle, Syddanmark, Denmark
Gandrup, Nordjylland, Denmark
Sapporo, Hokkaido, Japan
Kaohsiung Niao Sung Dist, Kaohsiung, Taiwan
Linz, Oberösterreich, Austria
Himeji, Hyogo, Japan
Minato Ku, Tokyo, Japan
São Paulo, , Brazil
São Paulo, , Brazil
Toronto, Ontario, Canada
Seoul, Seoul Teukbyeolsi [Seoul], Korea, Republic Of
Ostrava, Ostrava Město, Czechia
Diamondhead, Mississippi, United States
Esbjerg, Syddanmark, Denmark
Mattersburg, Burgenland, Austria
Oldenburg, Schleswig Holstein, Germany
Patras, Achaḯa, Greece
Afula, Hatsafon, Israel
Sakhnin, Hatsafon, Israel
Haifa, ḥeifā, Israel
Sapporo, Hokkaido, Japan
Shinjyuku Ku, Tokyo, Japan
Graz, Steiermark, Austria
Mechelen, Antwerpen, Belgium
Wrocław, Dolnośląskie, Poland
Warszawa, Mazowieckie, Poland
Centelles, Barcelona [Barcelona], Spain
Valencia, València, Spain
Bucharest, București, Romania
Bucharest, București, Romania
București, , Romania
York, North Yorkshire, United Kingdom
Madrid, , Spain
Enfield, England, United Kingdom
Sheffield, , United Kingdom
Ciudad Autonoma De Buenos Aires, Ciudad Autónoma De Buenos Aires, Argentina
Northridge, California, United States
Porto Alegre, Rio Grande Do Sul, Brazil
Baltimore, Maryland, United States
Lake Success, New York, United States
Rio De Janeiro, , Brazil
Beaver, Pennsylvania, United States
Tamarac, Florida, United States
Alken, Limburg, Belgium
Detroit, Michigan, United States
Chuo Ku, Tokyo, Japan
Hamburg, , Germany
La Coruña, A Coruña [La Coruña], Spain
Jacksonville, Florida, United States
Amersfoort, Utrecht, Netherlands
Albuquerque, New Mexico, United States
Meridian, Idaho, United States
Albany, New York, United States
New York, New York, United States
Avon, Indiana, United States
Rochester, New York, United States
Beachwood, Ohio, United States
Botany, New South Wales, Australia
Rio De Janeiro, , Brazil
São Paulo, , Brazil
São Paulo, , Brazil
Heidelberg West, Victoria, Australia
Joondalup, Western Australia, Australia
Joliette, Quebec, Canada
Brandýs Nad Labem Stará Boleslav, Praha Východ, Czechia
Nice, Alpes Maritimes, France
Marseille, Bouches Du Rhône, France
Beijing, Beijing, China
Budapest, , Hungary
Haifa, , Israel
Changzhou, Jiangsu, China
Elblag, Warmińsko Mazurskie, Poland
Rome, Lazio, Italy
Cinisello Balsamo, Milano, Italy
łódź, łódzkie, Poland
Pisa, , Italy
Cleveland, Ohio, United States
Vienna, Wien, Austria
București, , Romania
Belem, Pará, Brazil
Salzburg, , Austria
Beijing, Beijing, China
Votuporanga, São Paulo, Brazil
Oakville, Ontario, Canada
St. Thomas, Ontario, Canada
Lugo, Galicia [Galicia], Spain
Târgu Mureș, Mureș, Romania
Anchorage, Alaska, United States
Topeka, Kansas, United States
Franklin, Indiana, United States
Gelnhausen, Hessen, Germany
Köln, Nordrhein Westfalen, Germany
Budapest, , Hungary
Gent, Oost Vlaanderen, Belgium
Phoenix, Arizona, United States
Sant Joan Despí, Catalunya [Cataluña], Spain
Sevilla, , Spain
London, England, United Kingdom
Hull, Kingston Upon Hull, United Kingdom
Beijing, Beijing, China
Wonju, Kang Won Do, Korea, Republic Of
Den Bosch, Noord Brabant, Netherlands
Blackpool, Lancashire, United Kingdom
Amsterdam, Noord Holland, Netherlands
Hardenberg, Overijssel, Netherlands
Dothan, Alabama, United States
Brasília, Distrito Federal, Brazil
Mobile, Alabama, United States
Tucson, Arizona, United States
Tucson, Arizona, United States
Little Rock, Arkansas, United States
Anchorage, Alaska, United States
Beverly Hills, California, United States
Long Beach, California, United States
Covina, California, United States
Long Beach, California, United States
Huntington Beach, California, United States
Santa Clarita, California, United States
Los Angeles, California, United States
Sylmar, California, United States
San Diego, California, United States
Thousand Oaks, California, United States
Clearwater, Florida, United States
Thousand Oaks, California, United States
Hialeah, Florida, United States
Toluca Lake, California, United States
Port Charlotte, Florida, United States
Port Charlotte, Florida, United States
Jacksonville, Florida, United States
Jacksonville, Florida, United States
Douglasville, Georgia, United States
Gainesville, Georgia, United States
Port Orange, Florida, United States
Safety Harbor, Florida, United States
Lawrenceville, Georgia, United States
Macon, Georgia, United States
Tampa, Florida, United States
Lexington, Kentucky, United States
Woodstock, Georgia, United States
Honolulu, Hawaii, United States
Boise, Idaho, United States
Boston, Massachusetts, United States
Alexandria, Louisiana, United States
Dorchester, Massachusetts, United States
Lake Charles, Louisiana, United States
Monroe, Louisiana, United States
New Orleans, Louisiana, United States
Dearborn, Michigan, United States
Biloxi, Mississippi, United States
Gulfport, Mississippi, United States
Springfield, Missouri, United States
Slidell, Louisiana, United States
Bowie, Maryland, United States
Albuquerque, New Mexico, United States
Butte, Montana, United States
Kew Gardens, New York, United States
New York, New York, United States
Riverhead, New York, United States
Fayetteville, North Carolina, United States
Philadelphia, Pennsylvania, United States
Henderson, Nevada, United States
Las Vegas, Nevada, United States
Plymouth Meeting, Pennsylvania, United States
Charleston, South Carolina, United States
Las Vegas, Nevada, United States
Greenville, South Carolina, United States
Little River, South Carolina, United States
Mauldin, South Carolina, United States
Bridgeton, New Jersey, United States
Mount Pleasant, South Carolina, United States
Knoxville, Tennessee, United States
Memphis, Tennessee, United States
Amarillo, Texas, United States
Somerset, New Jersey, United States
Houston, Texas, United States
Dallas, Texas, United States
Houston, Texas, United States
Dallas, Texas, United States
Dallas, Texas, United States
Munro, Buenos Aires, Argentina
Mckinney, Texas, United States
Mckinney, Texas, United States
Mar Del Plata, Buenos Aires, Argentina
San Nicolas, Buenos Aires, Argentina
Buenos Aires, Ciudad Autónoma De Buenos Aires, Argentina
Buenos Aires, Ciudad Autónoma De Buenos Aires, Argentina
Buenos Aires, Ciudad Autónoma De Buenos Aires, Argentina
Mesquite, Texas, United States
Paraná, Entre Ríos, Argentina
Godoy Cruz, Mendoza, Argentina
Granadero Baigorria, Santa Fe, Argentina
Rosario, Santa Fe, Argentina
San Antonio, Texas, United States
San Antonio, Texas, United States
Sherman, Texas, United States
Rosario, Santa Fe, Argentina
Rosario, Santa Fe, Argentina
Morgantown, West Virginia, United States
Santa Fe, , Argentina
Rosario, Santa Fe, Argentina
Rosario, Santa Fe, Argentina
Brisbane, Queensland, Australia
Perth, Western Australia, Australia
Brisbane, Queensland, Australia
Herston, Queensland, Australia
Mount Isa, Queensland, Australia
Feldkirch, Vorarlberg, Austria
Vienna, Wien, Austria
Vienna, Wien, Austria
Salvador, Bahia, Brazil
Uberlandia, Minas Gerais, Brazil
Townsville, Queensland, Australia
Curitiba, Paraná, Brazil
Curitiba, Paraná, Brazil
Curitiba, Paraná, Brazil
Ribeirao Preto, São Paulo, Brazil
Adelaide, South Australia, Australia
Adelaide, South Australia, Australia
Adelaide, South Australia, Australia
Santo Andre, São Paulo, Brazil
Sao Bernardo Do Campo, São Paulo, Brazil
Asa Norte, , Brazil
Camberwell, Victoria, Australia
Geelong, Victoria, Australia
Melbourne, Victoria, Australia
Joondalup, Western Australia, Australia
Sao Paulo, São Paulo, Brazil
São José Dos Campos, São Paulo, Brazil
Tatui, São Paulo, Brazil
Rio De Janeiro, , Brazil
São Paulo, , Brazil
São Paulo, , Brazil
São Paulo, , Brazil
São Paulo, , Brazil
Victoria, British Columbia, Canada
Chicoutimi, Quebec, Canada
Victoria, British Columbia, Canada
Greenfield Park, Quebec, Canada
Winnipeg, Manitoba, Canada
Saint Charles Borromée, Quebec, Canada
Moncton, New Brunswick, Canada
Sydney, Nova Scotia, Canada
Wanzhou, Chongqing, China
Saint Jean Sur Richelieu, Quebec, Canada
Shenzhen, Guangdong, China
Quebec, , Canada
Luoyang, Henan, China
Hohhot, Inner Mongolia, China
Nanjing, Jiangsu, China
Chengdu, Sichuan, China
Tianjin, Tianjin, China
Urumchi, Xinjiang, China
Suzhou, Jiangsu, China
Urumqi, Xinjiang, China
Wuxi, Jiangsu, China
Jining, Shandong, China
Wenzhou, Zhejiang, China
Shanghai, , China
Trutnov, , Czechia
Zlín, , Czechia
Copenhagen, Hovedstaden, Denmark
Yinchuan, , China
Holbaek, Sjælland, Denmark
Aabenraa, Syddanmark, Denmark
Esbjerg, Syddanmark, Denmark
Brno, Brno Město, Czechia
Brno, Brno Město, Czechia
Asahikawa, Hokkaido, Japan
Komatsu, Ishikawa, Japan
Kanazawa, Ishikawa, Japan
Uchinada, Ishikawa, Japan
Morioka, Iwate, Japan
Kanazawa, Ishikawa, Japan
Takamatsu, Kagawa, Japan
Kanazawa, Ishikawa, Japan
Isehara, Kanagawa, Japan
Miyakonojo, Miyazaki, Japan
Matsumoto, Nagano, Japan
Kamakura Shi, Kanagawa, Japan
Ueda, Nagano, Japan
Nagaoka, Niigata, Japan
Naka Gun, Kanagawa, Japan
Chuo Ku, Tokyo, Japan
Kyoto, , Japan
Shinjyuku Ku, Tokyo, Japan
Kyoto, , Japan
Toshimaku, Tokyo, Japan
Toyoma, Toyama, Japan
Mobile, Alabama, United States
Gilbert, Arizona, United States
Escondido, California, United States
Fountain Valley, California, United States
Inglewood, California, United States
Lancaster, California, United States
Torrance, California, United States
Vista, California, United States
Columbus, Ohio, United States
La Jolla, California, United States
Mar Del Plata, Buenos Aires, Argentina
Denison, Texas, United States
Edinburg, Texas, United States
Quilmes, Buenos Aires, Argentina
Fort Worth, Texas, United States
Houston, Texas, United States
Park Ridge, Illinois, United States
Springfield, Illinois, United States
Ramos Mejía, Buenos Aires, Argentina
Buenos Aires, Ciudad Autónoma De Buenos Aires, Argentina
Winfield, Illinois, United States
Avon, Indiana, United States
Fort Washington, Maryland, United States
Franklin, Indiana, United States
Rio De Janeiro, , Brazil
Rio De Janeiro, , Brazil
São Paulo, , Brazil
Hamilton, Ontario, Canada
Columbus, Ohio, United States
Horsham, Pennsylvania, United States
Uniontown, Pennsylvania, United States
Yardley, Pennsylvania, United States
York, Pennsylvania, United States
Katowice, śląskie, Poland
San Antonio, Texas, United States
Wuhan, Hubei, China
Nanchang, Jiangxi, China
Xuzhou, Jiangsu, China
Redmond, Washington, United States
Del Viso, Buenos Aires, Argentina
Santa Fe, , Argentina
Dalian, Liaoning, China
Santa Fe, , Argentina
Ponce, , Puerto Rico
Shenandoah, Texas, United States
Sherman, Texas, United States
Botany, New South Wales, Australia
Clinton, Utah, United States
Norfolk, Virginia, United States
Changde, Hunan, China
Blumenau, Santa Catarina, Brazil
Aracaju, Sergipe, Brazil
Copenhagen, Hovedstaden, Denmark
Lanzhou, Gansu, China
Aarhus, Midtjylland, Denmark
Izumisano, Osaka, Japan
Suita Shi, Osaka, Japan
Monterrey, Nuevo León, Mexico
Lanzhou, Gansu, China
Monterrey, Nuevo León, Mexico
Foshan, Guangdong, China
Monterrey, Nuevo León, Mexico
Oaxaca De Juarez, Oaxaca, Mexico
Culiacan, Sinaloa, Mexico
Monterrey, Nuevo León, Mexico
Lublin, Lubelskie, Poland
Lublin, Lubelskie, Poland
Lublin, Lubelskie, Poland
Bayamón, , Puerto Rico
Taipei City, Taipei, Taiwan
Bialystok, Podlaskie, Poland
Taipei City, Taipei, Taiwan
Tainan, , Taiwan
Columbia, Maryland, United States
Taipei City, Taipei, Taiwan
Yilan City, Yilan, Taiwan
Kaohsiung, , Taiwan
Greensboro, North Carolina, United States
Greensboro, North Carolina, United States
San Luis Potosí, , Mexico
Mount Airy, North Carolina, United States
Beachwood, Ohio, United States
Veracruz, , Mexico
Sneek, Fryslân, Netherlands
Groningen, , Netherlands
Taoyuan, , Taiwan
Buenos Aires, Ciudad Autónoma De Buenos Aires, Argentina
Caba, Ciudad Autónoma De Buenos Aires, Argentina
Beverly Hills, California, United States
Wellington, Florida, United States
Bruce, Australian Capital Territory, Australia
Blacktown, New South Wales, Australia
Brookvale, New South Wales, Australia
Raleigh, North Carolina, United States
Wilmington, North Carolina, United States
Brussels, Bruxelles Capitale, Région De, Belgium
Huizhou, Guangdong, China
Prague, Praha 6, Czechia
Humble, Texas, United States
Prague, Praha, Hlavní Mešto, Czechia
Kobe, Hyogo, Japan
Miyazaki, , Japan
Zarow, Dolnośląskie, Poland
Takarazuka, Hyogo, Japan
Bydgoszcz, Kujawsko Pomorskie, Poland
Phoenix, Arizona, United States
Stamford, Connecticut, United States
Phoenix, Arizona, United States
Sun City West, Arizona, United States
Denver, Colorado, United States
Bowling Green, Kentucky, United States
Baltimore, Maryland, United States
Austin, Texas, United States
Ciudad De Buenos Aires, Buenos Aires, Argentina
Waterbury, Connecticut, United States
Buenos Aires, , Argentina
Corrientes, , Argentina
Córdoba, , Argentina
Córdoba, , Argentina
Córdoba, , Argentina
Córdoba, , Argentina
Rosario, Santa Fe, Argentina
Mendoza, , Argentina
Salta, , Argentina
Rosario, Santa Fe, Argentina
Merewether, New South Wales, Australia
Brisbane, Queensland, Australia
Venado Tuerto, Santa Fe, Argentina
Belo Horizonte, Minas Gerais, Brazil
Belo Horizonte, Minas Gerais, Brazil
Campinas, São Paulo, Brazil
Vancouver, British Columbia, Canada
London, Ontario, Canada
Frankfurt, Hessen, Germany
Gelnhausen, Hessen, Germany
Rüsselsheim, Hessen, Germany
Nasushiobara, Tochigi, Japan
Kozhikode, Kerala, India
Kanpur, Uttar Pradesh, India
Dehradun, Uttarakhand, India
Chuo Ku, Tokyo, Japan
Kasugai, Aichi, Japan
Daejeon, Taejǒn Kwangyǒkshi, Korea, Republic Of
Chuo Ku, Tokyo, Japan
Ulsan, , Korea, Republic Of
Guadalajara, Jalisco, Mexico
Guadalajara, Jalisco, Mexico
Guadalajara, Jalisco, Mexico
Morelia, Michoacán, Mexico
Cuernavaca, Morelos, Mexico
General Escobedo, Nuevo León, Mexico
Leszno, Wielkopolskie, Poland
Elblag, Warmińsko Mazurskie, Poland
Lodz, łódzkie, Poland
Lodz, łódzkie, Poland
Mcallen, Texas, United States
San Miguel De Tucuman, Tucumán, Argentina
San Miguel De Tucuman, Tucumán, Argentina
San Miguel De Tucuman, Tucumán, Argentina
Boca Raton, Florida, United States
Buenos Aires, , Argentina
Sydney, New South Wales, Australia
Niteroi, Rio De Janeiro, Brazil
Passo Fundo, Rio Grande Do Sul, Brazil
Chicago, Illinois, United States
Brampton, Ontario, Canada
London, Ontario, Canada
North York, Ontario, Canada
Québec, Quebec, Canada
Chicago, Illinois, United States
St Jerome, Quebec, Canada
Gurnee, Illinois, United States
Ningbo, Zhejiang, China
Lüneburg, Niedersachsen, Germany
Valenciennes, , France
Essen, Nordrhein Westfalen, Germany
Ulm, Baden Württemberg, Germany
Munich, Bayern, Germany
Münster, Nordrhein Westfalen, Germany
ōsaki, Miyagi, Japan
Takatsuki, Osaka, Japan
Nakano Ku, Tokyo, Japan
Potsdam, Brandenburg, Germany
Ootaku, Tokyo, Japan
Shinjuku Ku, Tokyo, Japan
Shunan, Yamaguchi, Japan
Aguascalientes, , Mexico
Chihuahua, , Mexico
Okayama, , Japan
Mexico City, Distrito Federal, Mexico
Monterrey, Nuevo León, Mexico
Querétaro, , Mexico
Elblag, Warmińsko Mazurskie, Poland
Lucenec, Banskobystrický Kraj, Slovakia
Trebisov, Košický Kraj, Slovakia
Buenos Aires, , Argentina
Orlando, Florida, United States
Orlando, Florida, United States
Acworth, Georgia, United States
Augusta, Georgia, United States
Campinas, São Paulo, Brazil
New Westminster, British Columbia, Canada
Guangzhou, Guangdong, China
Canton, Georgia, United States
West Des Moines, Iowa, United States
Topeka, Kansas, United States
Wichita, Kansas, United States
Kure, Hiroshima, Japan
Takasago, Hyogo, Japan
Tsuchiura, Ibaraki, Japan
Hakusan, Ishikawa, Japan
Birmingham, Alabama, United States
Ocala, Florida, United States
Indianapolis, Indiana, United States
Dallas, Texas, United States
Cincinnati, Ohio, United States
Ciudad Autonoma De Buenos Aires, Buenos Aires, Argentina
La Plata, Buenos Aires, Argentina
Buenos Aires, , Argentina
Santo Andre, São Paulo, Brazil
Brownsville, Texas, United States
Toronto, Ontario, Canada
Corpus Christi, Texas, United States
Dallas, Texas, United States
Szekesfehervar, Fejér, Hungary
Budapest, , Hungary
New Delhi, Delhi, India
Chikushino, Fukuoka, Japan
Nowa Sol, Lubuskie, Poland
Kitakyushu, Fukuoka, Japan
Târgu Mureș, Mureș, Romania
Hermosillo, Sonora, Mexico
Margate, Florida, United States
Merida, Yucatán, Mexico
Aguascalientes, , Mexico
Mckinney, Texas, United States
Alberdi, Córdoba, Argentina
Buenos Aires, , Argentina
Brisbane, Queensland, Australia
Mulgrave, Victoria, Australia
Porto Alegre, Rio Grande Do Sul, Brazil
Nagoya, Aichi, Japan
Asahi, Chiba, Japan
Miami Lakes, Florida, United States
Chuo, Yamanashi, Japan
Fukuoka, , Japan
Naples, Florida, United States
Okayama, , Japan
Mexico City, Distrito Federal, Mexico
Mexico City, Distrito Federal, Mexico
Monterrey, Nuevo León, Mexico
Ruda Slaska, śląskie, Poland
Tampa, Florida, United States
Osaka, , Japan
Troy, Michigan, United States
Warren, New Jersey, United States
Alamogordo, New Mexico, United States
Amarillo, Texas, United States
Hangzhou, Zhejiang, China
Osaka, , Japan
Tijuana, Baja California, Mexico
Querétaro, , Mexico
Lufkin, Texas, United States
Austin, Texas, United States
Houston, Texas, United States
Buenos Aires, , Argentina
Ostrava, Ostrava Město, Czechia
Surrey, British Columbia, Canada
Wuhan, Hubei, China
Marilia, São Paulo, Brazil
Suita, Osaka, Japan
Changchun, Jilin, China
Saint Ingbert, Saarland, Germany
Durango, , Mexico
Dabrowa Gornicza, śląskie, Poland
Tychy, śląskie, Poland
Buzau, Buzău, Romania
Tainan City, Tainan, Taiwan
Terrebonne, Quebec, Canada
Hamburg, , Germany
Kochi, Kerala, India
West Hills, California, United States
Perth, Western Australia, Australia
Yinchuan, Ningxia, China
Xi'an, Shaanxi, China
Kagoshima, , Japan
Kumamoto, , Japan
Kaohsiung, , Taiwan
Praha, Praha 4, Czechia
Maitland, Florida, United States
Seoul, Seoul Teukbyeolsi [Seoul], Korea, Republic Of
Dearborn, Michigan, United States
Seoul, Seoul Teukbyeolsi [Seoul], Korea, Republic Of
Summit, New Jersey, United States
Prague, Praha 4, Czechia
Taipei, , Taiwan
Torrance, California, United States
Trois Rivieres, Quebec, Canada
Taipei, , Taiwan
Shanghai, Shanghai, China
Taipei, , Taiwan
Shanghai, Shanghai, China
Bydgoszcz, Kujawsko Pomorskie, Poland
Lublin, Lubelskie, Poland
Tianjin, Tianjin, China
Krakow, Małopolskie, Poland
Cincinnati, Ohio, United States
Amarillo, Texas, United States
Prague, Praha 13, Czechia
Houston, Texas, United States
Groningen, , Netherlands
San Antonio, Texas, United States
Mexico City, Distrito Federal, Mexico
Târgu Mureș, Mureș, Romania
San Antonio, Texas, United States
Madrid, , Spain
Morgantown, West Virginia, United States
Ciudad De Buenos Aires, Buenos Aires, Argentina
Buenos Aires, Ciudad Autónoma De Buenos Aires, Argentina
Sevilla, , Spain
Preston, England, United Kingdom
Chengdu, Sichuan, China
Cheadle, Staffordshire, United Kingdom
Lishui, Zhejiang, China
Newcastle Upon Tyne, , United Kingdom
Utrecht, , Netherlands
Herlev, Hovedstaden, Denmark
Luoyang, Henan, China
Bridgeport, Connecticut, United States
Osaka, , Japan
Penticton, British Columbia, Canada
Nanyang, Henan, China
Osaka, , Japan
Saga, , Japan
Shanghai, Shanghai, China
Saitama, , Japan
Gouda, Zuid Holland, Netherlands
Atlanta, Georgia, United States
Zigong, Sichuan, China
Heidelberg, Baden Württemberg, Germany
Winston Salem, North Carolina, United States
Curitiba, Paraná, Brazil
Huntington Beach, California, United States
Beaver, Pennsylvania, United States
Dearborn, Michigan, United States
Gulfport, Mississippi, United States
Lanus, Buenos Aires, Argentina
Springfield, Missouri, United States
Las Vegas, Nevada, United States
Aguascalientes, , Mexico
Roeselare, West Vlaanderen, Belgium
Rosario, Santa Fe, Argentina
Townsville, Queensland, Australia
Jaén, , Spain
Newcastle Upon Tyne, England, United Kingdom
Daphne, Alabama, United States
Gilbert, Arizona, United States
West Des Moines, Iowa, United States
La Jolla, California, United States
Tucson, Arizona, United States
Van Nuys, California, United States
Largo, Florida, United States
Fall River, Massachusetts, United States
Shanghai, Shanghai, China
Quilmes, Buenos Aires, Argentina
Prague, Praha 2, Czechia
Oostende, West Vlaanderen, Belgium
Cheng Du, Sichuan, China
Vista, California, United States
Thessaloniki, Thessaloníki, Greece
Bologna, , Italy
Hakodate, Hokkaido, Japan
Sapporo, Hokkaido, Japan
Sapporo, Hokkaido, Japan
Isehara, Kanagawa, Japan
Sagamihara, Kanagawa, Japan
Fort Lauderdale, Florida, United States
Baltimore, Maryland, United States
Yokohama, Kanagawa, Japan
Kurashiki, Okayama, Japan
Chuo Ku, Tokyo, Japan
Budapest, , Hungary
Padova, Veneto, Italy
Meguro Ku, Tokyo, Japan
Kagoshima, , Japan
Vancouver, British Columbia, Canada
Guadalajara, Jalisco, Mexico
Hamilton, Ontario, Canada
Harbin, Heilongjiang, China
Lishui City, Zhejiang, China
Nachod, Královéhradecký Kraj, Czechia
Litovel, Olomoucký Kraj, Czechia
Olomouc, Olomoucký Kraj, Czechia
Prague, Praha 12, Czechia
Houston, Texas, United States
Bialystok, Podlaskie, Poland
Quincy, Massachusetts, United States
Brasov, Brașov, Romania
Glendale, Arizona, United States
Ciudad Autónoma De Buenos Aires, , Argentina
Baltimore, Maryland, United States
Glendale, Arizona, United States
Norwood, South Australia, Australia
Osaka, , Japan
Hodonin, Hodonín, Czechia
Patients applied
Trial Officials
1-877-CTLILLY (1-877-285-4559) or 317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST)
Study Director
Eli Lilly and Company
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported