A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)
Launched by ELI LILLY AND COMPANY · Mar 1, 2024
Trial Information
Current as of June 12, 2025
Recruiting
Keywords
ClinConnect Summary
The ACCLAIM-Lp(a) trial is studying a new treatment called lepodisiran to see if it can help reduce the risk of serious heart problems in adults who have high levels of a substance called lipoprotein(a), which can increase the chance of heart attacks and strokes. This study is specifically looking at adults who either already have heart disease or are at risk of developing it. If you are between 18 and 74 years old and have high lipoprotein(a) levels, you might qualify to participate.
Participants in this study will receive the treatment through an injection under the skin. The trial is currently recruiting, and it’s important to note that certain health conditions may prevent someone from joining, such as recent major heart events or uncontrolled high blood pressure. If you decide to participate, you’ll have the opportunity to contribute to important research that could help others at risk for heart disease.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Have Lipoprotein(a) \[Lp(a)\] ≥175 nanomoles per liter (nmol/L).
- * Meet criteria of either 2a or 2b:
- • 2a: Individuals 18 years of age or older with established atherosclerotic cardiovascular disease (ASCVD) with an event or revascularization.
- • 2b: Individuals 55 years of age or older who are at risk for a first cardiovascular (CV) event and either: Documented coronary artery disease (CAD), carotid stenosis, or peripheral artery disease (PAD) without history of event or revascularization; known familial hypercholesteremia; or a combination of high-risk factors.
- Exclusion Criteria:
- • Have had a major cardiovascular event or surgery, such as myocardial infarction (MI), stroke or coronary or peripheral revascularization, \< 60 days before screening
- • Have uncontrolled hypertension
- • Have New York Heart Association class IV heart failure.
- • Have lipoprotein apheresis within 90 days of screening, or planned lipoprotein apheresis during the study.
- • Have severe renal failure, defined as
- • Estimated glomerular rate (eGFR) \<15 milliliters per minute per 1.73 meters squared (mL/min/1.73m2) at screening Visit 1, or ongoing dialysis.
- • Have a diagnosis of active nephrotic syndrome, or urine albumin-creatinine ratio (UACR) of ≥5000 mg/g at screening Visit 1.
- • Have acute or chronic hepatitis, known cirrhosis, signs and symptoms of any other liver disease other than metabolic-associated steatotic liver disease, or exclusionary laboratory results as determined by the central laboratory during screening.
About Eli Lilly And Company
Eli Lilly and Company is a global healthcare leader dedicated to creating innovative medicines that improve patient outcomes across a range of therapeutic areas, including diabetes, oncology, immunology, and neurodegenerative diseases. With a rich history of scientific research and a commitment to advancing healthcare, Lilly invests significantly in clinical trials to develop new treatments and enhance existing therapies. The company prioritizes patient safety and ethical standards in its clinical research, fostering collaboration with healthcare professionals and stakeholders to ensure the delivery of high-quality, evidence-based solutions that address unmet medical needs worldwide.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Columbus, Ohio, United States
Bridgeport, Connecticut, United States
Detroit, Michigan, United States
Rochester, New York, United States
Baltimore, Maryland, United States
Atlanta, Georgia, United States
Liverpool, New South Wales, Australia
Madrid, , Spain
Zaragoza, , Spain
Perth, Western Australia, Australia
Stanford, California, United States
Brisbane, Queensland, Australia
Cleveland, Ohio, United States
Washington, District Of Columbia, United States
Honolulu, Hawaii, United States
Jacksonville, Florida, United States
Dallas, Texas, United States
Stevenage, Hertfordshire, United Kingdom
New York, New York, United States
Little Rock, Arkansas, United States
Madrid, , Spain
Murray, Utah, United States
Baltimore, Maryland, United States
Lancaster, Pennsylvania, United States
Winnipeg, Manitoba, Canada
Geelong, Victoria, Australia
Santander, Cantabria, Spain
Jaén, , Spain
Las Palmas De Gran Canaria, Las Palmas, Spain
Gijón, Asturias, Spain
Osaka, , Japan
Amsterdam, Noord Holland, Netherlands
Leiden, Zuid Holland, Netherlands
Milano, , Italy
Haifa, , Israel
Kanazawa, Ishikawa, Japan
Uchinada, Ishikawa, Japan
Sevilla, , Spain
San Antonio, Texas, United States
Tainan, , Taiwan
Segovia, , Spain
Sevilla, , Spain
Kaohsiung, , Taiwan
Seoul, , Korea, Republic Of
Sapporo, Hokkaido, Japan
Anchorage, Alaska, United States
Porto Alegre, Rio Grande Do Sul, Brazil
Waterbury, Connecticut, United States
Baltimore, Maryland, United States
Berlin, , Germany
Mobile, Alabama, United States
Uniontown, Pennsylvania, United States
Tucson, Arizona, United States
Jacksonville, Florida, United States
Woodstock, Georgia, United States
Leipzig, Sachsen, Germany
Seoul, , Korea, Republic Of
Torrance, California, United States
Kanazawa, Ishikawa, Japan
Takamatsu, Kagawa, Japan
Matsumoto, Nagano, Japan
Kurashiki, Okayama, Japan
Izumisano, Osaka, Japan
Nanjing, Jiangsu, China
Kaohsiung, , Taiwan
Magdeburg, Sachsen Anhalt, Germany
Hamilton, Ontario, Canada
New York, New York, United States
Butte, Montana, United States
Stanford, California, United States
Gilbert, Arizona, United States
San Antonio, Texas, United States
Shanghai, , China
Allentown, Pennsylvania, United States
La Plata, Buenos Aires, Argentina
Tampa, Florida, United States
Townsville, Queensland, Australia
Padova, Veneto, Italy
Budapest, , Hungary
Winston Salem, North Carolina, United States
Taipei, , Taiwan
Nagoya, Aichi, Japan
Morioka, Iwate, Japan
Isehara, Kanagawa, Japan
Okayama, , Japan
Meguro Ku, Tokyo, Japan
Beijing, Beijing, China
Quebec, , Canada
Kyoto, , Japan
Torquay, Devon, United Kingdom
Taoyuan, , Taiwan
Beijing, Beijing, China
La Jolla, California, United States
Utrecht, , Netherlands
Blackpool, Lancashire, United Kingdom
Graz, Steiermark, Austria
Kobe, Hyogo, Japan
Eindhoven, Noord Brabant, Netherlands
Chuo, Yamanashi, Japan
Aachen, Nordrhein Westfalen, Germany
Phoenix, Arizona, United States
Harbin, Heilongjiang, China
Wuhan, Hubei, China
Port Orange, Florida, United States
Zhengzhou, Henan, China
Wuhan, Hubei, China
Wuxi, Jiangsu, China
Nanchang, Jiangxi, China
Xi'an, Shaanxi, China
Shanghai, Shanghai, China
Edegem, Antwerpen, Belgium
Taipei, , Taiwan
Sylmar, California, United States
Albuquerque, New Mexico, United States
Santa Fe, , Argentina
Chengdu, Sichuan, China
Nanchang, Jiangxi, China
Beijing, Beijing, China
Tianjin, Tianjin, China
Falls Church, Virginia, United States
Leuven, Vlaams Brabant, Belgium
Aurora, Colorado, United States
Stony Brook, New York, United States
Topeka, Kansas, United States
Sagamihara, Kanagawa, Japan
Osaka, , Japan
Hangzhou, Zhejiang, China
Lanzhou, Gansu, China
Chengdu, Sichuan, China
Atlanta, Georgia, United States
Suzhou, Jiangsu, China
Meadowbrook, Queensland, Australia
Palm Springs, California, United States
Greenfield Park, Quebec, Canada
New York, New York, United States
Miami, Florida, United States
Apeldoorn, Gelderland, Netherlands
Lanzhou, Gansu, China
Kitakyushu, Fukuoka, Japan
Saga, , Japan
Salford, Manchester, United Kingdom
Madrid, , Spain
Kanazawa, Ishikawa, Japan
Alexandria, Louisiana, United States
Camp Hill, Pennsylvania, United States
Changsha, Hunan, China
Debrecen, , Hungary
Guangzhou, Guangdong, China
Beijing, Beijing, China
Shanghai, Shanghai, China
Dendermonde, Oost Vlaanderen, Belgium
Pisa, , Italy
Luoyang, Henan, China
Hohhot, Inner Mongolia, China
Regensburg, Bayern, Germany
Sapporo, Hokkaido, Japan
Camberwell, Victoria, Australia
Northridge, California, United States
Somerset, New Jersey, United States
Chicoutimi, Quebec, Canada
Indianapolis, Indiana, United States
Yinchuan, , China
Beijing, Beijing, China
Den Bosch, Noord Brabant, Netherlands
Takarazuka, Hyogo, Japan
Lugo, , Spain
Budapest, , Hungary
Venado Tuerto, Santa Fe, Argentina
Nanjing, Jiangsu, China
Hangzhou, Zhejiang, China
San Diego, California, United States
Wenzhou, Zhejiang, China
Harbin, Heilongjiang, China
Beverly Hills, California, United States
Guangzhou, Guangdong, China
Munich, Bayern, Germany
Xuzhou, Jiangsu, China
Szeged, Csongrád, Hungary
Urumqi, Xinjiang, China
Hamburg, , Germany
Cheng Du, Sichuan, China
Ningbo, Zhejiang, China
Haifa, ḥeifā, Israel
Phoenix, Arizona, United States
West Des Moines, Iowa, United States
Baltimore, Maryland, United States
Groningen, , Netherlands
Nanjing, Jiangsu, China
Jena, Thüringen, Germany
Gent, Oost Vlaanderen, Belgium
São Paulo, , Brazil
Nanjing, Jiangsu, China
Rotterdam, Zuid Holland, Netherlands
Philadelphia, Pennsylvania, United States
Ulsan, , Korea, Republic Of
Orlando, Florida, United States
Margate, Florida, United States
Ypsilanti, Michigan, United States
Amarillo, Texas, United States
Rosario, Santa Fe, Argentina
Surrey, British Columbia, Canada
Yinchuan, Ningxia, China
Valenciennes, , France
Aguascalientes, , Mexico
Bydgoszcz, Kujawsko Pomorskie, Poland
Gdańsk, Pomorskie, Poland
Stamford, Connecticut, United States
Brisbane, Queensland, Australia
Nijmegen, Gelderland, Netherlands
Chuo Ku, Tokyo, Japan
Mexico, Distrito Federal, Mexico
Beaver, Pennsylvania, United States
Cleveland, Ohio, United States
West Bromwich, , United Kingdom
Heidelberg West, Victoria, Australia
Greenville, North Carolina, United States
Yueyang, Hunan, China
Siping, Jilin, China
Greensboro, North Carolina, United States
Changchun, Jilin, China
Hasselt, Limburg, Belgium
Suita, Osaka, Japan
Kochi, Kerala, India
Besançon, Doubs, France
Rosario, Santa Fe, Argentina
Osaka, , Japan
Saint Peters, Missouri, United States
Jerusalem, Yerushalayim, Israel
Potsdam, Brandenburg, Germany
Lishui, Zhejiang, China
Paris, île De France, France
Las Vegas, Nevada, United States
Jinan, Shandong, China
Ocala, Florida, United States
Porto Alegre, Rio Grande Do Sul, Brazil
Rapid City, South Dakota, United States
Fukuoka, , Japan
Baggiovara, Modena, Italy
Gainesville, Georgia, United States
Minato Ku, Tokyo, Japan
Salzburg, , Austria
Lancaster, California, United States
Macon, Georgia, United States
Mexico City, Distrito Federal, Mexico
Pozuelo De Alarcón, Madrid, Spain
Boca Raton, Florida, United States
Shinjyuku Ku, Tokyo, Japan
Mannheim, Baden Württemberg, Germany
Shanghai, Shanghai, China
Paris, , France
Mckinney, Texas, United States
Berlin, , Germany
Huntington Beach, California, United States
Hellerup, , Denmark
Nice, Alpes Maritimes, France
Lucknow, Uttar Pradesh, India
Tsuchiura, Ibaraki, Japan
Zaandam, Noord Holland, Netherlands
Lufkin, Texas, United States
Deventer, Overijssel, Netherlands
Los Angeles, California, United States
Yokohama, Kanagawa, Japan
Fall River, Massachusetts, United States
Huizhou, Guangdong, China
Houston, Texas, United States
Milan, Milano, Italy
Covina, California, United States
West Hills, California, United States
Avon, Indiana, United States
Jingzhou, Hubei, China
Kasugai, Aichi, Japan
Victoria, British Columbia, Canada
Trutnov, , Czechia
Toronto, Ontario, Canada
Wichita, Kansas, United States
Chuo Ku, Tokyo, Japan
Phoenix, Arizona, United States
Braunau, Oberösterreich, Austria
Seongnam, Kyǒnggi Do, Korea, Republic Of
Naples, Florida, United States
Morgantown, West Virginia, United States
Saratoga Springs, New York, United States
Houston, Texas, United States
Sherman, Texas, United States
Firenze, Toscana, Italy
Brasschaat, Antwerpen, Belgium
Vista, California, United States
Guangzhou, Guangdong, China
Columbus, Ohio, United States
Milan, Milano, Italy
Zigong, Sichuan, China
Takasago, Hyogo, Japan
Gent, Oost Vlaanderen, Belgium
Olomouc, , Czechia
Oldenburg, Schleswig Holstein, Germany
Porto Alegre, Rio Grande Do Sul, Brazil
Long Beach, California, United States
New Delhi, Delhi, India
Tianjin, Tianjin, China
Vancouver, British Columbia, Canada
Linz, Oberösterreich, Austria
Québec, Quebec, Canada
Madrid, , Spain
Ponce, , Puerto Rico
Clearwater, Florida, United States
Asahikawa, Hokkaido, Japan
Seoul, Seoul Teukbyeolsi [Seoul], Korea, Republic Of
Brno, Brno Město, Czechia
Beijing, Beijing, China
Pau, Pyrénées Atlantiques, France
Amsterdam, Noord Holland, Netherlands
San Antonio, Texas, United States
Kortrijk, West Vlaanderen, Belgium
San Juan, , Puerto Rico
Thousand Oaks, California, United States
Copenhagen, Hovedstaden, Denmark
Botany, New South Wales, Australia
Wien, , Austria
Leeuwarden, Fryslân, Netherlands
Montpellier, Hérault, France
Monterrey, Nuevo León, Mexico
Beachwood, Ohio, United States
Hefei, Anhui, China
Dalian, Liaoning, China
Houston, Texas, United States
São Paulo, , Brazil
Anchorage, Alaska, United States
Miami Lakes, Florida, United States
Seoul, Seoul Teukbyeolsi [Seoul], Korea, Republic Of
Malaga, Andalucía, Spain
Madrid, Madrid, Comunidad De, Spain
Salamanca, , Spain
Taipei City, Taipei, Taiwan
Aarhus, Midtjylland, Denmark
Nîmes, Gard, France
Takatsuki, Osaka, Japan
Gurnee, Illinois, United States
Guadalajara, Jalisco, Mexico
Beverwijk, Noord Holland, Netherlands
Botany, New South Wales, Australia
Brasov, Brașov, Romania
Mobile, Alabama, United States
Shanghai, Shanghai, China
Kumamoto, , Japan
Suita Shi, Osaka, Japan
Blumenau, Santa Catarina, Brazil
Campinas, São Paulo, Brazil
Marilia, São Paulo, Brazil
Monterrey, Nuevo León, Mexico
Cordoba, Andalucía, Spain
Nashik, Maharashtra, India
Edinburg, Texas, United States
Okayama, , Japan
Rotterdam, Zuid Holland, Netherlands
Ramat Gan, Hamerkaz, Israel
Kfar Saba, Hamerkaz, Israel
Greensboro, North Carolina, United States
Mcallen, Texas, United States
Bonheiden, Antwerpen, Belgium
Brasília, Distrito Federal, Brazil
Santo Andre, São Paulo, Brazil
New Westminster, British Columbia, Canada
Prague, Praha 2, Czechia
București, , Romania
Shavano Park, Texas, United States
London, Ontario, Canada
Haifa, ḥeifā, Israel
Guadalajara, Jalisco, Mexico
Bologna, , Italy
Corvallis, Oregon, United States
Newcastle Upon Tyne, England, United Kingdom
Blacktown, New South Wales, Australia
Kanwal, New South Wales, Australia
Hialeah, Florida, United States
Mckinney, Texas, United States
Wien, , Austria
Chicago, Illinois, United States
Pittsburgh, Pennsylvania, United States
Amarillo, Texas, United States
Mesquite, Texas, United States
Antwerp, Antwerpen, Belgium
Harderwijk, Gelderland, Netherlands
Changhua County, Changhua, Taiwan
San Antonio, Texas, United States
Lake Success, New York, United States
Clinton, Utah, United States
Mexico City, Distrito Federal, Mexico
Wellington, Florida, United States
Troy, Michigan, United States
Springfield, Missouri, United States
Las Vegas, Nevada, United States
Greenville, South Carolina, United States
Caba, Buenos Aires, Argentina
Merewether, New South Wales, Australia
Wien, , Austria
São Paulo, , Brazil
North York, Ontario, Canada
Shenyang, Liaoning, China
Gelnhausen, Hessen, Germany
Essen, Nordrhein Westfalen, Germany
Münster, Nordrhein Westfalen, Germany
Paleo Faliro, Attikí (Region), Greece
Chaidari, Attikí, Greece
Thessaloniki, Kentrikí Makedonía, Greece
Budapest, , Hungary
Chuo Ku, Tokyo, Japan
Ootaku, Tokyo, Japan
Cuernavaca, Morelos, Mexico
Merida, Yucatán, Mexico
Ede, Gelderland, Netherlands
Krakow, Małopolskie, Poland
Katowice, śląskie, Poland
Bucharest, București, Romania
Malacky, Bratislavský Kraj, Slovakia
Rožňava, Košický Kraj, Slovakia
łódź, łódzkie, Poland
Saint Charles Borromée, Quebec, Canada
Wichita, Kansas, United States
Knoxville, Tennessee, United States
Taipei, , Taiwan
Dresden, Sachsen, Germany
Jaén, , Spain
Hartford, Connecticut, United States
Preston, England, United Kingdom
Ueda, Nagano, Japan
Miyazaki, , Japan
Sanlúcar De Barrameda, Cádiz, Spain
Gilly, Hainaut, Belgium
Plymouth Meeting, Pennsylvania, United States
Fort Lauderdale, Florida, United States
Macon, Georgia, United States
Saint Ingbert, Saarland, Germany
Mesquite, Texas, United States
Raleigh, North Carolina, United States
New Orleans, Louisiana, United States
Buenos Aires, , Argentina
Budapest, , Hungary
Dallas, Texas, United States
Komatsu, Ishikawa, Japan
Vienna, Wien, Austria
Rehovot, Hamerkaz, Israel
Norfolk, Virginia, United States
Henderson, Nevada, United States
Springfield, Illinois, United States
Brussels, Bruxelles Capitale, Région De, Belgium
Brussels, Bruxelles Capitale, Région De, Belgium
São José Do Rio Preto, São Paulo, Brazil
Osaka, , Japan
Nanyang, Henan, China
Kenosha, Wisconsin, United States
Rosario, Santa Fe, Argentina
San Nicolas, Buenos Aires, Argentina
Sao Paulo, São Paulo, Brazil
Tainan City, Tainan, Taiwan
Franklin, Indiana, United States
Biloxi, Mississippi, United States
Philadelphia, Pennsylvania, United States
Vitória, Espírito Santo, Brazil
Curitiba, Paraná, Brazil
Hyattsville, Maryland, United States
Rosario, Santa Fe, Argentina
Mechelen, Antwerpen, Belgium
Wilmington, North Carolina, United States
Charleroi, Hainaut, Belgium
Redmond, Washington, United States
Xi'an, Shaanxi, China
Seoul, Seoul Teukbyeolsi [Seoul], Korea, Republic Of
Brasov, , Romania
Port Charlotte, Florida, United States
Kamakura Shi, Kanagawa, Japan
Shinjuku Ku, Tokyo, Japan
Brookvale, New South Wales, Australia
Roeselare, West Vlaanderen, Belgium
Patras, Achaḯa, Greece
Yokosuka, Kanagawa, Japan
Amersfoort, Utrecht, Netherlands
Badalona, Barcelona [Barcelona], Spain
Rouen, Haute Normandie, France
Chuo Ku, Tokyo, Japan
Rio De Janeiro, , Brazil
Largo, Florida, United States
Safety Harbor, Florida, United States
Bossier City, Louisiana, United States
Corrientes, , Argentina
Goiania, Goiás, Brazil
Wuhan, Hubei, China
Changchun, Jilin, China
Urumchi, Xinjiang, China
Petah Tikva, Hamerkaz, Israel
Haifa, Hatsafon, Israel
Nahariya, Hatsafon, Israel
Jerusalem, Yerushalayim, Israel
Guadalajara, Jalisco, Mexico
Monterrey, Nuevo León, Mexico
Aguascalientes, , Mexico
Querétaro, , Mexico
San Antonio, Texas, United States
Oaxaca De Juarez, Oaxaca, Mexico
Seoul, Seoul Teukbyeolsi [Seoul], Korea, Republic Of
San Antonio, Texas, United States
Namdong Gu, Incheon Gwangyeoksi [Incheon], Korea, Republic Of
Den Haag, Zuid Holland, Netherlands
Barcelona, Catalunya [Cataluña], Spain
Bruce, Australian Capital Territory, Australia
Harbin, Heilongjiang, China
Toshimaku, Tokyo, Japan
Genova, Liguria, Italy
Seoul, Seoul Teukbyeolsi [Seoul], Korea, Republic Of
Girona, Girona [Gerona], Spain
Santa Clarita, California, United States
Tamarac, Florida, United States
Lake Charles, Louisiana, United States
New York, New York, United States
Mauldin, South Carolina, United States
Morgantown, West Virginia, United States
Lexington, Kentucky, United States
Mar Del Plata, Buenos Aires, Argentina
Vancouver, British Columbia, Canada
Avon, Indiana, United States
Canton, Georgia, United States
Buenos Aires, , Argentina
Copenhagen, Hovedstaden, Denmark
Petah Tikva, Hamerkaz, Israel
Tel Aviv, Tell Abīb, Israel
Palma, Balears [Baleares], Spain
Barcelona, Barcelona [Barcelona], Spain
Barcelona, Catalunya [Cataluña], Spain
El Palmar, Murcia, Murcia, Región De, Spain
Reus, Tarragona [Tarragona], Spain
Santiago De Compostela, A Coruña [La Coruña], Spain
Passo Fundo, Rio Grande Do Sul, Brazil
Be'er Sheva, Hadarom, Israel
Albany, New York, United States
Godoy Cruz, Mendoza, Argentina
Wonju, Kang Won Do, Korea, Republic Of
Seoul, Seoul Teukbyeolsi [Seoul], Korea, Republic Of
Lublin, Lubelskie, Poland
Dolny Kubin, žilinský Kraj, Slovakia
Seville, Sevilla, Spain
Taichung City, Taichung, Taiwan
New Taipei, , Taiwan
São Paulo, , Brazil
Wuhu, Anhui, China
Brno, Brno Město, Czechia
Culiacan, Sinaloa, Mexico
Lublin, Lubelskie, Poland
Morayfield, Queensland, Australia
Paris, île De France, France
Dallas, Texas, United States
Escondido, California, United States
Bowling Green, Kentucky, United States
Rio De Janeiro, , Brazil
Dresden, Sachsen, Germany
Votuporanga, São Paulo, Brazil
Kagoshima, , Japan
Mexico City, Distrito Federal, Mexico
Mexico City, Distrito Federal, Mexico
Guadalajara, Jalisco, Mexico
San Nicolas De Los Garza, Nuevo León, Mexico
Holon, Hamerkaz, Israel
Pisa, Toscana, Italy
Galați, , Romania
Satu Mare, , Romania
Hull, Kingston Upon Hull, United Kingdom
Córdoba, , Argentina
Ferrol, A Coruña [La Coruña], Spain
Veracruz, , Mexico
Ribeirao Preto, São Paulo, Brazil
Changchun, Jilin, China
Strasbourg, Alsace, France
Querétaro, , Mexico
Venlo, Limburg, Netherlands
Valencia, Valenciana, Comunitat, Spain
Taipei City, Taipei, Taiwan
Himeji, Hyogo, Japan
Houston, Texas, United States
Belagavi, Karnataka, India
Delft, Zuid Holland, Netherlands
Vienna, Wien, Austria
Brownsville, Texas, United States
Yardley, Pennsylvania, United States
Shenandoah, Texas, United States
Del Viso, Buenos Aires, Argentina
Lanus, Buenos Aires, Argentina
Mar Del Plata, Buenos Aires, Argentina
Granadero Baigorria, Santa Fe, Argentina
Rosario, Santa Fe, Argentina
Rosario, Santa Fe, Argentina
Rosario, Santa Fe, Argentina
San Miguel De Tucuman, Tucumán, Argentina
San Miguel De Tucuman, Tucumán, Argentina
Córdoba, , Argentina
Córdoba, , Argentina
Mendoza, , Argentina
Santa Fe, , Argentina
Adelaide, South Australia, Australia
Joondalup, Western Australia, Australia
Innsbruck, Tirol, Austria
Feldkirch, Vorarlberg, Austria
Oostende, West Vlaanderen, Belgium
Niteroi, Rio De Janeiro, Brazil
Sao Bernardo Do Campo, São Paulo, Brazil
São Paulo, , Brazil
Moncton, New Brunswick, Canada
Terrebonne, Quebec, Canada
Xian, Shaanxi, China
Ostrava, Ostrava Město, Czechia
Zlín, , Czechia
Le Coudray, Eure Et Loir, France
Bad Homburg, Hessen, Germany
Athens, Attikí, Greece
Athens, Attikí, Greece
Ioannina, Ioánnina, Greece
Heraklion, Irakleío, Greece
Thessaloniki, Thessaloníki, Greece
Bikaner, Rajasthan, India
Sakhnin, Hatsafon, Israel
Ferrara, Emilia Romagna, Italy
Seoul, Seoul Teukbyeolsi [Seoul], Korea, Republic Of
Tijuana, Baja California, Mexico
Mexico City, Distrito Federal, Mexico
Guadalajara, Jalisco, Mexico
Guadalajara, Jalisco, Mexico
Hermosillo, Sonora, Mexico
Aguascalientes, , Mexico
Durango, , Mexico
Haarlem, Noord Holland, Netherlands
Groningen, , Netherlands
Bydgoszcz, Kujawsko Pomorskie, Poland
Elblag, Warmińsko Mazurskie, Poland
Bucharest, București, Romania
Craiova, Dolj, Romania
Baia Mare, Maramureș, Romania
Baia Mare, Maramureș, Romania
Târgu Mureș, Mureș, Romania
Târgu Mureș, Mureș, Romania
Timisoara, Timiș, Romania
Timișoara, Timiș, Romania
Galați, , Romania
Iași, , Romania
Sibiu, , Romania
Dolny Kubin, žilinský Kraj, Slovakia
Martin, žilinský Kraj, Slovakia
Villamartin, Cádiz, Spain
Alcorcón, Madrid, Comunidad De, Spain
Kaohsiung Niao Sung Dist, Kaohsiung, Taiwan
Vienna, Wien, Austria
Köln, Nordrhein Westfalen, Germany
Aracaju, Sergipe, Brazil
São Paulo, , Brazil
Changzhou, Jiangsu, China
Nyiregyhaza, Nyíregyháza, Hungary
Mexico City, Distrito Federal, Mexico
San Luis Potosí, , Mexico
Tampa, Florida, United States
Herlev, Hovedstaden, Denmark
Vejle, Syddanmark, Denmark
Frankfurt, Hessen, Germany
Bielefeld, Nordrhein Westfalen, Germany
Berlin, , Germany
Hardenberg, Overijssel, Netherlands
Gouda, Zuid Holland, Netherlands
Târgu Mureș, Mureș, Romania
Iași, , Romania
L'hospitalet De Llobregat, Catalunya [Cataluña], Spain
Rio De Janeiro, , Brazil
Rio De Janeiro, , Brazil
Fountain Valley, California, United States
Sao Paulo, São Paulo, Brazil
Zalaegerszeg, Zala, Hungary
Marseille, Bouches Du Rhône, France
Gilbert, Arizona, United States
Nantes Cedex 1, Loire Atlantique, France
Santa Fe, , Argentina
Curitiba, Paraná, Brazil
Tatui, São Paulo, Brazil
Chikushino, Fukuoka, Japan
Caba, Ciudad Autónoma De Buenos Aires, Argentina
Pessac, Aquitaine, France
Salta, , Argentina
Boston, Massachusetts, United States
Toronto, Ontario, Canada
Campinas, São Paulo, Brazil
Fort Washington, Maryland, United States
Trois Rivieres, Quebec, Canada
Rosario, Santa Fe, Argentina
Hakodate, Hokkaido, Japan
Kagoshima, , Japan
Corpus Christi, Texas, United States
Franklin, Indiana, United States
Dothan, Alabama, United States
New York, New York, United States
Baltimore, Maryland, United States
Dorchester, Massachusetts, United States
Changde, Hunan, China
Chicago, Illinois, United States
Ramos Mejía, Buenos Aires, Argentina
Huntington Beach, California, United States
Bobigny, île De France, France
Warren, New Jersey, United States
Long Beach, California, United States
Adelaide, South Australia, Australia
Kosice, Košický Kraj, Slovakia
Trebisov, Košický Kraj, Slovakia
Bucharest, București, Romania
Beaver, Pennsylvania, United States
Den Bosch, Noord Brabant, Netherlands
Isehara, Kanagawa, Japan
Río Cuarto, Córdoba, Argentina
Wonju, Kang Won Do, Korea, Republic Of
Gandrup, Nordjylland, Denmark
Albuquerque, New Mexico, United States
Sherman, Texas, United States
Bad Friedrichshall, , Germany
Prague, Praha 13, Czechia
Clayton, Victoria, Australia
Belo Horizonte, Minas Gerais, Brazil
Budapest, , Hungary
Cheng Du, Sichuan, China
Sun City West, Arizona, United States
Denison, Texas, United States
Buenos Aires, , Argentina
Linz, Oberösterreich, Austria
Brno, Brno Město, Czechia
León, Guanajuato, Mexico
Lubochna, žilinský Kraj, Slovakia
Bologna, , Italy
Joondalup, Western Australia, Australia
Przemysl, Podkarpackie, Poland
Daphne, Alabama, United States
Lille, Nord, France
Uberlandia, Minas Gerais, Brazil
Nice, Alpes Maritimes, France
Bratislava, Bratislavský Kraj, Slovakia
Beverly Hills, California, United States
Raipur, Chhattisgarh, India
Summit, New Jersey, United States
Brasilia, Distrito Federal, Brazil
Bequimao, Maranhão, Brazil
Buenos Aires, , Argentina
Piešťany, Trnavský Kraj, Slovakia
Santo Andre, São Paulo, Brazil
Ciudad De Buenos Aires, Buenos Aires, Argentina
Victoria, British Columbia, Canada
Monterrey, Nuevo León, Mexico
Toluca Lake, California, United States
Suwon Si, Kyǒnggi Do, Korea, Republic Of
Lanus, Buenos Aires, Argentina
Inglewood, California, United States
Daejeon, Taejǒn Kwangyǒkshi, Korea, Republic Of
Sheffield, , United Kingdom
Foshan, Guangdong, China
Monroe, Louisiana, United States
Elblag, Warmińsko Mazurskie, Poland
Columbus, Ohio, United States
San Miguel De Tucuman, Tucumán, Argentina
Rosario, Santa Fe, Argentina
Hull, Kingston Upon Hull, United Kingdom
Bridgeton, New Jersey, United States
Sippy Downs, Queensland, Australia
Jacksonville, Florida, United States
Topeka, Kansas, United States
Saint Jean Sur Richelieu, Quebec, Canada
Paris, Orne, France
Springfield, Missouri, United States
Heidelberg, Baden Württemberg, Germany
Curitiba, Paraná, Brazil
Krakow, Małopolskie, Poland
Buenos Aires, Ciudad Autónoma De Buenos Aires, Argentina
Buenos Aires, Ciudad Autónoma De Buenos Aires, Argentina
Ciudad De Buenos Aires, Buenos Aires, Argentina
Buenos Aires, Ciudad Autónoma De Buenos Aires, Argentina
Ciudad Autonoma De Buenos Aires, Ciudad Autónoma De Buenos Aires, Argentina
Ciudad Autónoma De Buenos Aires, Buenos Aires, Argentina
Dénia, Alicante, Spain
Orlando, Florida, United States
Padova, Veneto, Italy
Köln, Nordrhein Westfalen, Germany
Shinjyuku Ku, Tokyo, Japan
Berlin, , Germany
Chambray Les Tours, Centre, France
Warsaw, Mazowieckie, Poland
Daegu, Taegu Kwangyǒkshi, Korea, Republic Of
Elblag, Warmińsko Mazurskie, Poland
Bialystok, Podlaskie, Poland
Genk, Limburg, Belgium
Nitra, Nitriansky Kraj, Slovakia
Mount Pleasant, South Carolina, United States
Lüneburg, Niedersachsen, Germany
Afula, Hatsafon, Israel
Xalapa, Veracruz, Mexico
Doetinchem, Gelderland, Netherlands
Dearborn, Michigan, United States
Monterrey, Nuevo León, Mexico
São Paulo, , Brazil
Beachwood, Ohio, United States
Praha, Praha 4, Czechia
Fayetteville, North Carolina, United States
Sosa Gu, Kyǒnggi Do, Korea, Republic Of
Brasília, Distrito Federal, Brazil
Mechelen, Antwerpen, Belgium
Nasushiobara, Tochigi, Japan
Nanyang, Henan, China
Cincinnati, Ohio, United States
Cincinnati, Ohio, United States
Quilmes, Buenos Aires, Argentina
Warszawa, Mazowieckie, Poland
Porto Alegre, Rio Grande Do Sul, Brazil
Houston, Texas, United States
Perth, Western Australia, Australia
Dehradun, Uttarakhand, India
Austin, Texas, United States
Gwangju Si, Kwangju Kwangyǒkshi, Korea, Republic Of
Oakville, Ontario, Canada
Van Nuys, California, United States
Austin, Texas, United States
Târgu Mureș, Mureș, Romania
Mexico City, Distrito Federal, Mexico
Bron, Rhône, France
Dresden, Sachsen, Germany
Baltimore, Maryland, United States
São Paulo, , Brazil
St Jerome, Quebec, Canada
Chihuahua, , Mexico
Uherské Hradiště, Zlínský Kraj, Czechia
Cheadle, Staffordshire, United Kingdom
Bayamón, , Puerto Rico
Herlev, Hovedstaden, Denmark
Rio De Janeiro, , Brazil
Lublin, Lubelskie, Poland
Warsaw, Mazowieckie, Poland
łódź, łódzkie, Poland
Bydgoszcz, Kujawsko Pomorskie, Poland
Clearwater, Florida, United States
Torrance, California, United States
Buenos Aires, Ciudad Autónoma De Buenos Aires, Argentina
Córdoba, , Argentina
Rochdale, Manchester, United Kingdom
Tucson, Arizona, United States
Ostrava, Ostrava Město, Czechia
Bucharest, București, Romania
Hamburg, , Germany
Indianapolis, Indiana, United States
Esbjerg, Syddanmark, Denmark
Dongjak Gu, Seoul Teukbyeolsi [Seoul], Korea, Republic Of
Little River, South Carolina, United States
Humble, Texas, United States
Simi Valley, California, United States
Birmingham, Alabama, United States
Peoria, Arizona, United States
Phoenix, Arizona, United States
Los Angeles, California, United States
Thousand Oaks, California, United States
Vista, California, United States
Denver, Colorado, United States
Maitland, Florida, United States
Port Charlotte, Florida, United States
Acworth, Georgia, United States
Augusta, Georgia, United States
Douglasville, Georgia, United States
Lawrenceville, Georgia, United States
Boise, Idaho, United States
Park Ridge, Illinois, United States
Winfield, Illinois, United States
Slidell, Louisiana, United States
Bowie, Maryland, United States
Columbia, Maryland, United States
Dearborn, Michigan, United States
Gulfport, Mississippi, United States
Las Vegas, Nevada, United States
Alamogordo, New Mexico, United States
Kew Gardens, New York, United States
Riverhead, New York, United States
Mount Airy, North Carolina, United States
Horsham, Pennsylvania, United States
York, Pennsylvania, United States
Charleston, South Carolina, United States
Memphis, Tennessee, United States
Amarillo, Texas, United States
Austin, Texas, United States
Dallas, Texas, United States
Dallas, Texas, United States
Fort Worth, Texas, United States
Houston, Texas, United States
Mckinney, Texas, United States
Ciudad Autonoma De Buenos Aires, Buenos Aires, Argentina
Munro, Buenos Aires, Argentina
San Martín, Buenos Aires, Argentina
Buenos Aires, Ciudad Autónoma De Buenos Aires, Argentina
Buenos Aires, Ciudad Autónoma De Buenos Aires, Argentina
Alberdi, Córdoba, Argentina
Paraná, Entre Ríos, Argentina
Buenos Aires, , Argentina
Buenos Aires, , Argentina
Sydney, New South Wales, Australia
Brisbane, Queensland, Australia
Brisbane, Queensland, Australia
Herston, Queensland, Australia
Mount Isa, Queensland, Australia
Adelaide, South Australia, Australia
Melbourne, Victoria, Australia
Mulgrave, Victoria, Australia
Vienna, Wien, Austria
Maceio, Alagoas, Brazil
Salvador, Bahia, Brazil
Salvador, Bahia, Brazil
Belo Horizonte, Minas Gerais, Brazil
Belo Horizonte, Minas Gerais, Brazil
Curitiba, Paraná, Brazil
Belem, Pará, Brazil
São José Dos Campos, São Paulo, Brazil
Asa Norte, , Brazil
Rio De Janeiro, , Brazil
São Paulo, , Brazil
Sydney, Nova Scotia, Canada
Brampton, Ontario, Canada
London, Ontario, Canada
St. Thomas, Ontario, Canada
Hefei, Anhui, China
Chongqing, Chongqing, China
Wanzhou, Chongqing, China
Shenzhen, Guangdong, China
Jining, Shandong, China
Lishui City, Zhejiang, China
Brno, Brno Město, Czechia
Nachod, Královéhradecký Kraj, Czechia
Litovel, Olomoucký Kraj, Czechia
Olomouc, Olomoucký Kraj, Czechia
Prague, Praha 12, Czechia
Prague, Praha 4, Czechia
Prague, Praha 6, Czechia
Prague, Praha, Hlavní Mešto, Czechia
Brandýs Nad Labem Stará Boleslav, Praha Východ, Czechia
Kolin, Středočeský Kraj, Czechia
Ricany, Středočeský Kraj, Czechia
Holbaek, Sjælland, Denmark
Aabenraa, Syddanmark, Denmark
Ulm, Baden Württemberg, Germany
Rüsselsheim, Hessen, Germany
Remscheid, Nordrhein Westfalen, Germany
Leipzig, Sachsen, Germany
Szekesfehervar, Fejér, Hungary
Budapest, , Hungary
Kozhikode, Kerala, India
Kanpur, Uttar Pradesh, India
Asahi, Chiba, Japan
Kure, Hiroshima, Japan
Hakodate, Hokkaido, Japan
Sapporo, Hokkaido, Japan
Hakusan, Ishikawa, Japan
Naka Gun, Kanagawa, Japan
ōsaki, Miyagi, Japan
Miyakonojo, Miyazaki, Japan
Matsumoto, Nagano, Japan
Nagaoka, Niigata, Japan
Sunto Gun, Shizuoka, Japan
Nakano Ku, Tokyo, Japan
Toyoma, Toyama, Japan
Shunan, Yamaguchi, Japan
Kyoto, , Japan
Saitama, , Japan
Daegu, Taegu Kwangyǒkshi, Korea, Republic Of
Mexico City, Distrito Federal, Mexico
Tlalpan, Distrito Federal, Mexico
Guadalajara, Jalisco, Mexico
Morelia, Michoacán, Mexico
General Escobedo, Nuevo León, Mexico
Monterrey, Nuevo León, Mexico
Sneek, Fryslân, Netherlands
Zarow, Dolnośląskie, Poland
Grudziadz, Kujawsko Pomorskie, Poland
Lublin, Lubelskie, Poland
Nowa Sol, Lubuskie, Poland
Chrzanow, Małopolskie, Poland
Krakow, Małopolskie, Poland
Tarnow, Małopolskie, Poland
Kedzierzyn Kozle, Opolskie, Poland
Leszno, Wielkopolskie, Poland
Lodz, łódzkie, Poland
Lodz, łódzkie, Poland
Bielsko Biala, śląskie, Poland
Dabrowa Gornicza, śląskie, Poland
Ruda Slaska, śląskie, Poland
Tychy, śląskie, Poland
Buzau, Buzău, Romania
Lucenec, Banskobystrický Kraj, Slovakia
Rimavská Sobota, Banskobystrický Kraj, Slovakia
Presov, Prešovský Kraj, Slovakia
Trstena, žilinský Kraj, Slovakia
Taipei City, Taipei, Taiwan
Yilan City, Yilan, Taiwan
London, England, United Kingdom
Glasgow, Scotland, United Kingdom
Tyne And Wear, , United Kingdom
Sant Joan Despí, Catalunya [Cataluña], Spain
La Jolla, California, United States
Atlanta, Georgia, United States
Beltsville, Maryland, United States
Sherman, Texas, United States
Mistelbach, Niederösterreich, Austria
St. Polten, Niederösterreich, Austria
Brussels, Bruxelles Capitale, Région De, Belgium
Salvador, Bahia, Brazil
Brasilia, Distrito Federal, Brazil
Recife, Pernambuco, Brazil
Porto Alegre, Rio Grande Do Sul, Brazil
Sao Paulo, São Paulo, Brazil
São Paulo, , Brazil
Xiamen, Fujian, China
Nanning, Guangxi, China
Chifeng, Inner Mongolia, China
Tianjin, Tianjin, China
Brno, Brno Město, Czechia
Marseille, Bouches Du Rhône, France
Dijon, Bourgogne, France
Rennes, Bretagne, France
Toulouse, Haute Garonne, France
Compiègne, Oise, France
Lyon, Rhône Alpes, France
Mannheim, Baden Württemberg, Germany
Athens, Attikí, Greece
Balatongyorok, Veszprém, Hungary
Rome, Lazio, Italy
Cinisello Balsamo, Milano, Italy
Pisa, Toscana, Italy
Arzignano, Veneto, Italy
Perugia, , Italy
Miyakonojo, Miyazaki, Japan
Bucheon Si, Kyǒnggi Do, Korea, Republic Of
Ciudad De México, Distrito Federal, Mexico
Amersfoort, Utrecht, Mexico
Gouda, Zuid Holland, Mexico
Utrecht, , Mexico
Roosendaal, Noord Brabant, Netherlands
Tilburg, Noord Brabant, Netherlands
Veldhoven, Noord Brabant, Netherlands
Hilversum, Noord Holland, Netherlands
Goes, Zeeland, Netherlands
Wrocław, Dolnośląskie, Poland
Warszawa, Mazowieckie, Poland
Presov, Prešovský Kraj, Slovakia
A Coruña, A Coruña [La Coruña], Spain
Granada, Andalucía, Spain
Majadahonda, Madrid, Comunidad De, Spain
Valencia, Valenciana, Comunitat, Spain
Valencia, València, Spain
Huelva, , Spain
Bristol, Bristol, City Of, United Kingdom
Bialystok, Podlaskie, Poland
Luoyang, Henan, China
Penticton, British Columbia, Canada
Chuo Ku, Tokyo, Japan
Joliette, Quebec, Canada
Ciudad Autónoma De Buenos Aires, , Argentina
Warsaw, Mazowieckie, Poland
Westlake Village, California, United States
Dearborn, Michigan, United States
Brasília, Distrito Federal, Brazil
Morgantown, West Virginia, United States
Torrance, California, United States
Meridian, Idaho, United States
Gulfport, Mississippi, United States
Las Vegas, Nevada, United States
Buenos Aires, Ciudad Autónoma De Buenos Aires, Argentina
São Paulo, , Brazil
Shanghai, Shanghai, China
Brandýs Nad Labem Stará Boleslav, Praha Východ, Czechia
Gelnhausen, Hessen, Germany
Budapest, , Hungary
Rome, Lazio, Italy
Amsterdam, Noord Holland, Netherlands
Lublin, Lubelskie, Poland
Târgu Mureș, Mureș, Romania
Sant Joan Despí, Catalunya [Cataluña], Spain
Lugo, Galicia [Galicia], Spain
London, England, United Kingdom
Oostende, West Vlaanderen, Belgium
Quilmes, Buenos Aires, Argentina
Madrid, , Spain
Sevilla, , Spain
Newcastle Upon Tyne, , United Kingdom
Alexandria, Louisiana, United States
Adelaide, South Australia, Australia
Townsville, Queensland, Australia
Houston, Texas, United States
Thessaloniki, Thessaloníki, Greece
Ciudad Autónoma De Buenos Aires, , Argentina
South Brisbane, Queensland, Australia
Norwood, South Australia, Australia
Hamilton, Ontario, Canada
Tucson, Arizona, United States
Vancouver, British Columbia, Canada
Glendale, Arizona, United States
Osaka, , Japan
Alken, Limburg, Belgium
Quincy, Massachusetts, United States
West Des Moines, Iowa, United States
Glendale, Arizona, United States
Hodonin, Hodonín, Czechia
Diamondhead, Mississippi, United States
Mattersburg, Burgenland, Austria
Mechelen, Antwerpen, Belgium
Ostrava, Ostrava Město, Czechia
Esbjerg, Syddanmark, Denmark
Sapporo, Hokkaido, Japan
Wrocław, Dolnośląskie, Poland
Bucharest, București, Romania
Bucharest, București, Romania
București, , Romania
La Coruña, A Coruña [La Coruña], Spain
Centelles, Barcelona [Barcelona], Spain
Valencia, València, Spain
Enfield, England, United Kingdom
York, North Yorkshire, United Kingdom
Uherske Hradiste, Zlínský Kraj, Czechia
Orlando, Florida, United States
Sherman, Texas, United States
Meadowbrook, Queensland, Australia
Noosaville, Queensland, Australia
Brno, Brno Město, Czechia
Granada, Andalucía, Spain
Patients applied
Trial Officials
1-877-CTLILLY (1-877-285-4559) or 317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST)
Study Director
Eli Lilly and Company
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported