Implementation of Lung Cancer Screening in the First Line Zone of ZORA (Flanders), Using a Low Dose CT-scan

Launched by UNIVERSITY HOSPITAL, ANTWERP · Feb 27, 2024

Keywords

ClinConnect Summary

A four year prospective non-randomized feasibility implementation study for lung cancer screening in a targeted high-risk population of heavy (ex-)smokers by low-dose CT, combined with a smoking cessation intervention. It will be coordinated by a consortium of researchers from UZA and UAntwerpen.

Lung cancer (LC) remains the leading cause of cancer mortality, worldwide and in Belgium. Prevention and early detection are considered the cornerstones to increase the chances of successful treatment and improved outcomes. There is strong scientific evidence that screening for lung cancer through...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • The target population consists of all adult inhabitants from the following municipalities of the ELZ ZORA: Mortsel (2640), Edegem (2650), Boechout (2530), Kontich (2550), Lint (2547), Hove (2540), and having a (TBA) % risk of developing an incidental lung cancer in the following 6 years (calculated a by risk prediction model)
• • 1. Males and females
• • 2. 55 -74 years old
• • 3. Fitness for any kind of curative therapy for lung cancer
• • 4. Absence of prior (lung) cancer in the 5 preceding years (excluding skin basal cell carcinoma and early stage cervical cancer)
• • 5. Having a GP or related trusted health care provider
• Exclusion Criteria:
• • 1. participant may not have any symptoms (cough, pain when breathing in...)
• • 2. Body weight \>140 kg in view of the maximum charge of the CT-scan table
• • 3. The (rare) hereditary Li-Fraumeni syndrome which gives the carriers an excess risk of X-ray induced oncogenesis