Pleurodesis Using Hypertonic Glucose
Launched by LONDON HEALTH SCIENCES CENTRE RESEARCH INSTITUTE OR LAWSON RESEARCH INSTITUTE OF ST. JOSEPH'S · Mar 1, 2024
Trial Information
Current as of July 01, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at a treatment called pleurodesis using a solution of Dextrose, which is a type of sugar, to help fix air leaks from the lungs after surgery. Air leaks can happen when the lungs do not heal properly after surgeries to remove parts of the lung, and they can be quite common, affecting about 10% of patients who have major lung surgeries. The study aims to see if giving Dextrose directly into the chest area can help close these leaks and promote healing.
To participate in this trial, you must be an adult patient scheduled for surgery to remove part of your lung due to cancer and have a significant air leak that is measured on the first day after your surgery. The trial is not yet recruiting participants, but it is open to all genders, and there are no specific exclusion criteria. If you are eligible and choose to participate, you will receive the Dextrose treatment and be monitored to see how well it works in helping to close the air leak and support your recovery.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Adult patients undergoing scheduled pulmonary lobar or sublobar resection for cancer
- • Presence of air leak on postoperative day 1 of at least 100 mL/min, as documented on the digital drainage system
- Exclusion Criteria:
- • - None
About London Health Sciences Centre Research Institute Or Lawson Research Institute Of St. Joseph's
The London Health Sciences Centre Research Institute, affiliated with Lawson Health Research Institute at St. Joseph's Health Care, is dedicated to advancing healthcare through innovative research and clinical trials. With a focus on translating scientific discoveries into practical applications, the institute fosters collaboration among leading researchers, clinicians, and healthcare professionals. It aims to improve patient outcomes and enhance the quality of care through rigorous investigation in areas such as cancer, cardiovascular health, and neuroscience. By integrating cutting-edge research with clinical practice, the institute plays a pivotal role in shaping the future of healthcare delivery in the community and beyond.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
London, Ontario, Canada
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported