Effects of Relighting on Smoke Toxicant Deliveries and Subjective Smoking Measures

Launched by MASONIC CANCER CENTER, UNIVERSITY OF MINNESOTA · Feb 29, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how relighting cigarettes affects the amount of harmful substances smokers inhale and how they feel about their smoking experience. Researchers will study a group of 30 smokers who often relight their cigarettes. They will compare the smoke produced by cigarettes that are relit with those that are smoked continuously without relighting, both in everyday settings and in a research clinic. The hope is to find out if relit cigarettes are more dangerous due to higher levels of toxic substances.

To participate in this study, you need to be a smoker who has been smoking at least 10 cigarettes a day for over a year and regularly relights your cigarettes. You should not have tried to quit smoking in the past month or plan to quit in the next month. It's also important that you have stable health conditions and are not dealing with substance abuse issues. If you decide to join, you will undergo various assessments to measure your smoking habits and the smoke produced by both types of cigarettes. This research aims to provide better insights into smoking behaviors and their impact on health.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Smoking at least 10 cigarettes/day for at least 1 year (confirmed by CO \> 8 ppm or NicAlert test of 6)
• • Engaging in relighting for at least half of their CPD
• • No smoking quit attempts in the past month nor intentions to quit in the next month
• • Stable medical or psychiatric conditions with systolic blood pressure \< 160, diastolic blood pressure \< 100 and heart rate \< 105 bpm
• Exclusion Criteria:
• • Participant with current or recent alcohol or drug abuse problems, use of substances of abuse (other than marijuana due to high prevalence of co-use) within the past month
• • Currently trying or planning to quit smoking in the next month
• • Planning to become pregnant, pregnant or breastfeeding. Pregnancy exclusion will be confirmed through a urine test.