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Search / Trial NCT06296173

Open Lung Protective Extubation Following General Anesthesia

Launched by CENTRE HOSPITALIER DE L'UNIVERSITÉ DE MONTRÉAL (CHUM) · Feb 28, 2024

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is studying a new approach to help people breathe better after having surgery under general anesthesia, particularly for those undergoing intra-abdominal procedures. The goal is to see if a special breathing technique, called "open lung" ventilation, can reduce problems that may occur in the lungs after surgery, such as a condition where parts of the lungs collapse (called atelectasis). Researchers want to determine the best way to help keep the lungs well-aerated immediately after the breathing tube is removed, which is known as extubation.

To participate in this trial, patients need to be adults who are scheduled for elective surgery on their abdomen and are considered at moderate to high risk for lung complications based on a specific scoring system. They should expect to be monitored closely during the study to assess their lung function after surgery. It’s important to note that patients with certain complications, such as expected difficult intubation or those who might need mechanical ventilation afterward, would not be eligible for the trial. This research aims to improve practices during surgery to help patients recover better and have fewer lung issues postoperatively.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Adult patients (18 years of age or over)
  • Elective intra-abdominal surgery under general anesthesia.
  • Moderate or high risk of postoperative pulmonary complication according to the ARISCAT score (score of 26 or more)
  • Planned postoperative hospitalization
  • Exclusion Criteria:
  • Expected or known difficult intubation according to the treating anesthesiologist
  • Postoperative mechanical ventilation (planned or unplanned)
  • General anesthesia performed outside the main operating room

About Centre Hospitalier De L'université De Montréal (Chum)

The Centre Hospitalier de l'Université de Montréal (CHUM) is a leading academic health institution in Canada, dedicated to advancing patient care through innovative research and clinical excellence. As a prominent sponsor of clinical trials, CHUM is committed to leveraging its multidisciplinary expertise and state-of-the-art facilities to facilitate groundbreaking studies that enhance medical knowledge and improve health outcomes. Collaborating with a network of healthcare professionals and researchers, CHUM fosters a rigorous research environment that prioritizes patient safety, ethical standards, and scientific integrity, positioning itself at the forefront of medical advancements.

Locations

Ottawa, Ontario, Canada

Montréal, Quebec, Canada

Québec, , Canada

Toronto, Ontario, Canada

Patients applied

0 patients applied

Trial Officials

Martin Girard, MD

Principal Investigator

Centre hospitalier de l'Université de Montréal (CHUM)

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported