Open Lung Protective Extubation Following General Anesthesia
Launched by CENTRE HOSPITALIER DE L'UNIVERSITÉ DE MONTRÉAL (CHUM) · Feb 28, 2024
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying a new approach to help people breathe better after having surgery under general anesthesia, particularly for those undergoing intra-abdominal procedures. The goal is to see if a special breathing technique, called "open lung" ventilation, can reduce problems that may occur in the lungs after surgery, such as a condition where parts of the lungs collapse (called atelectasis). Researchers want to determine the best way to help keep the lungs well-aerated immediately after the breathing tube is removed, which is known as extubation.
To participate in this trial, patients need to be adults who are scheduled for elective surgery on their abdomen and are considered at moderate to high risk for lung complications based on a specific scoring system. They should expect to be monitored closely during the study to assess their lung function after surgery. It’s important to note that patients with certain complications, such as expected difficult intubation or those who might need mechanical ventilation afterward, would not be eligible for the trial. This research aims to improve practices during surgery to help patients recover better and have fewer lung issues postoperatively.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Adult patients (18 years of age or over)
- • Elective intra-abdominal surgery under general anesthesia.
- • Moderate or high risk of postoperative pulmonary complication according to the ARISCAT score (score of 26 or more)
- • Planned postoperative hospitalization
- Exclusion Criteria:
- • Expected or known difficult intubation according to the treating anesthesiologist
- • Postoperative mechanical ventilation (planned or unplanned)
- • General anesthesia performed outside the main operating room
About Centre Hospitalier De L'université De Montréal (Chum)
The Centre Hospitalier de l'Université de Montréal (CHUM) is a leading academic health institution in Canada, dedicated to advancing patient care through innovative research and clinical excellence. As a prominent sponsor of clinical trials, CHUM is committed to leveraging its multidisciplinary expertise and state-of-the-art facilities to facilitate groundbreaking studies that enhance medical knowledge and improve health outcomes. Collaborating with a network of healthcare professionals and researchers, CHUM fosters a rigorous research environment that prioritizes patient safety, ethical standards, and scientific integrity, positioning itself at the forefront of medical advancements.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Ottawa, Ontario, Canada
Montréal, Quebec, Canada
Québec, , Canada
Toronto, Ontario, Canada
Patients applied
Trial Officials
Martin Girard, MD
Principal Investigator
Centre hospitalier de l'Université de Montréal (CHUM)
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported