Acceleration Time Assessment for Prediction of Critical Limb Ischemia

Launched by CENTRE HOSPITALIER LE MANS · Feb 29, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new and easy way to diagnose Critical Limb Ischemia (CLI), a serious condition where blood flow to the legs is severely reduced, leading to pain or wounds. The goal is to create a reliable tool that can help doctors identify patients with CLI quickly, so they can receive the necessary treatment sooner. Researchers hope that by using advanced ultrasound techniques, they can better assess the blood flow in the legs and make the diagnosis process easier and more accurate.

To participate in this trial, you need to be at least 18 years old and have been referred to a vascular medicine department for an ultrasound of your lower limbs. You should also have evidence of arterial disease, either showing symptoms or not. Unfortunately, if you have certain conditions, like being unstable or have already scheduled surgery on your legs, you won't be able to participate. If you join the trial, expect to undergo some tests that measure blood flow, helping doctors understand your condition better. This study aims to enhance the way CLI is diagnosed, ultimately improving patient care.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥ 18 years;
• • Patient referred to the vascular medicine department of one of the investigating centres for arterial Doppler ultrasound of at least one lower limb and for whom a measurement of the systolic pressure index at the toe will be performed.
• * Presence of proven arterial disease, asymptomatic or not, defined by the presence of one of the following criteria:
• • Rest ankle systolic pressure index ≤ 0.90
• • Rest toe systolic pressure index ≤ 0.70
• Exclusion Criteria:
• • Patient with haemodynamic instability, unable to tolerate a delay in therapeutic management caused by the ultrasound examination and measurement of systolic pressure at the toe;
• • Patients with surgical management of the lower limb (in relation to lower limb arteriopathy), already scheduled at the time of inclusion.
• • Patients with a life expectancy of less than 24 hours;
• • History of transmetatarsal amputation or amputation at a more proximal level compromising the measurement of systolic pressure and occlusion at the toe and/or TCPO2;
• • Refusal to participate