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Search / Trial NCT06298370

The Efficacy of Combined Intrathecal Morphine and PENG Block on Postoperative Pain in Hip Arthroplasty

Launched by BEZMIALEM VAKIF UNIVERSITY · Mar 5, 2024

Trial Information

Current as of July 26, 2025

Recruiting

Keywords

Postoperative Pain Intrathecal Morphine Intrathecal Bupivacaine Hip Arthroplasty Pericapsular Nerve Group Block

ClinConnect Summary

This clinical trial is studying how well a combination of two pain management techniques—low-dose intrathecal morphine (a pain medicine given through the spine) and a specific nerve block called the Pericapsular Nerve Group (PENG) block—works in managing pain after hip surgery. Researchers want to see if this combination can reduce the amount of morphine needed and improve recovery compared to using either method alone. The trial is currently looking for participants aged 18 to 90 who are undergoing hip replacement surgery and meet specific health criteria.

If you join the study, you will receive one of the pain management treatments during your surgery and will be monitored for 48 hours afterward to evaluate your pain levels and recovery. To be eligible, you should not have a history of opioid addiction, certain serious health conditions, or allergies to the medications being used. This trial aims to help improve pain management strategies for patients undergoing hip surgeries, making recovery smoother and more comfortable.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Aged between 18 and 90 years
  • American Society of Anesthesiologists (score ranging from 1 to 4)
  • Anterior hip arthroplasties
  • Exclusion Criteria:
  • Patients with a history of opioid addiction
  • Individuals under the age of 18
  • Those aged 90 and above
  • Allergies to morphine, fentanyl, bupivacaine, or tramadol
  • Coagulopathy
  • Infection at the injection site
  • Severe cardiac, renal, or hepatic dysfunction
  • Cases unable to provide informed consent
  • Body Mass Index \>40 kg/m2
  • Known neurological or anatomical deficits in the lower extremities
  • Patients requiring a transition from spinal anesthesia to general anesthesia

About Bezmialem Vakif University

Bezmialem Vakif University is a prominent academic institution based in Istanbul, Turkey, dedicated to advancing medical research and education. As a clinical trial sponsor, the university leverages its state-of-the-art facilities and a multidisciplinary team of experts to conduct innovative research that aims to improve patient outcomes and enhance therapeutic strategies. Bezmialem Vakif University is committed to adhering to rigorous ethical standards and regulatory guidelines, ensuring the integrity and reliability of its clinical trials while fostering collaboration with global research communities. Through its initiatives, the university seeks to contribute significantly to the field of medicine and public health.

Locations

Istanbul, Fatih, Turkey

Patients applied

0 patients applied

Trial Officials

Saadet Oztop, MD

Principal Investigator

Bezmialem Vakif University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported