The Effect of Three Different Medications on Anesthetic Success and Postoperative Pain
Launched by CAIRO UNIVERSITY · Mar 5, 2024
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at how three different medications can help with pain control during and after dental treatment for people suffering from symptomatic irreversible pulpitis, a condition causing severe tooth pain. The goal is to find a safer and more effective way to manage pain, allowing for a more comfortable experience during dental procedures.
To participate, you need to be between 65 and 74 years old and have moderate to severe pain in your lower back teeth. You must be able to understand pain scales and agree to join the study. However, if you have allergies to the medications used, are pregnant or breastfeeding, or have taken pain medication within the last 12 hours, you won’t be eligible. If you join the trial, you can expect to receive one of the medications and be monitored for how well it helps with pain management. This trial aims to improve pain relief methods for dental treatments and ensure a better experience for patients.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients with symptomatic irreversible pulpitis.
- • Patients with active pain (moderate-to-severe) in mandibular molars.
- • Males and females.
- • Patient with the ability to understand and use pain scales.
- • Patient who accepts to enroll to the study
- Exclusion Criteria:
- • Patients' allergies or any other contraindication to any of the used medications or mepivacaine.
- • Pregnant and lactating females.
- • Patients have been taking pain medication 12 hours earlier.
- • Patient has more than one symptomatic mandibular tooth in the same quadrant.
- • Patients with periradicular pathosis and/or radiolucency other than widened periodontal ligaments.
- • Patients with contributory medical history (ASA\>II).
About Cairo University
Cairo University, a premier institution in Egypt, is dedicated to advancing medical research and education through innovative clinical trials. With a strong emphasis on improving healthcare outcomes, the university collaborates with various stakeholders to conduct rigorous scientific studies that address critical health challenges. Leveraging its extensive resources and expert faculty, Cairo University aims to contribute valuable insights to the medical community and enhance patient care both locally and globally. Through its commitment to ethical research practices and excellence, the university plays a pivotal role in shaping the future of healthcare in the region.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Badr City, Cairo, Egypt
Cairo, , Egypt
Cairo, , Egypt
Patients applied
Trial Officials
Maha Nasr
Principal Investigator
Egyptian Russian University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported