Bowel Preparation for Colonoscopy Among Individuals With Crohn's and Ulcerative Colitis Disease.

Launched by UNIVERSITY OF MANITOBA · Feb 29, 2024

Keywords

ClinConnect Summary

This clinical trial is exploring the best way for people with Crohn's disease or ulcerative colitis to prepare their bowels before having a colonoscopy, which is a procedure that allows doctors to examine the inside of the colon. The study will compare two types of laxatives: an oral sulfate solution (OSS) and a 2-liter polyethylene glycol (PEG) solution. Researchers want to find out which laxative is more effective and easier for patients to handle.

To be eligible for this study, participants must be at least 18 years old, have Crohn's disease or ulcerative colitis, and be scheduled for a colonoscopy. However, some people cannot participate, such as those who have had certain types of bowel surgery or have specific health issues like kidney problems or severe heart conditions. Those who join the trial can expect to take one of the two laxatives before their colonoscopy, and their experiences will help doctors improve bowel preparation for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Crohn's disease or ulcerative colitis patients scheduled or about to be scheduled for colonoscopy.
• • 2. Age \> 18 years
• • 3. Out-patients
• Exclusion Criteria:
• • 1. Prior subtotal or total colorectal resection
• • 2. Contraindications to use of 2L polyethylene glycol (2L-PEG) or Oral Sulfate Solution (OSS): Known renal insufficiency, congestive heart failure, cirrhosis, severe electrolyte imbalance.
• • 3. Colonoscopy being repeated because of poor preparation in the preceding six months.
• • 4. Allergies to the employed bowel preparations
• • 5. Toxic megacolon, ileus, suspected or diagnosed bowel obstruction.
• • 6. IBD patients thought to be too sick to undergo a full colonoscopy preparation in the opinion of the investigator/treating physician; hospitalized crohn's disease or ulcerative colitis patients.
• • 7. Pregnancy