The Pattern of Dry Eye Disease After Cataract Surgery

Launched by LITHUANIAN UNIVERSITY OF HEALTH SCIENCES · Mar 1, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how dry eye disease (DED) develops after cataract surgery. Researchers want to understand the changes in the eye's surface and how patients feel about their dry eye symptoms over time. They will also look at the relationship between these symptoms and signs of inflammation in the eye, as well as pain levels, particularly considering the use of artificial tears for lubrication.

To be eligible for the trial, participants need to be between 50 and 90 years old and have undergone cataract surgery performed by the same experienced surgeon without any complications. They should not have any pre-existing eye conditions or have had any previous eye surgeries. Participants can expect to share their experiences and undergo some tests during the study to help researchers gather valuable information about dry eye disease following cataract surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Cataract patients from 50 to 90 years old who underwent uncomplicated phacoemulsification performed by one (and same) experienced surgeon.
• • Patients with no underlying ocular surface diseases (keratitis, keratoconjunctivitis and others).
• • Patients who previously did not undergo any ophthalmic surgery.
• Exclusion Criteria:
• • Patient expressed his wish to not participate in the study or discontinue it when already enrolled.
• • Severe dry eye disease diagnosed with OSDI/DEQ-5 and at least one of the following tests: TBUT less than 10 seconds, tear osmolarity higher than 308 mOsm/l or positive corneal staining.
• • Glaucoma.
• • Diabetes mellitus.
• • Systemic connective tissue disease, autoimmune disease.
• • Neurologic conditions including stroke, Bell's palsy, Parkinson's, trigeminal nerve dysfunction.
• • Patients who underwent refractive surgery (LASIK or PRK).
• • Contact lens users.
• • One or more of the following concomitant medications: psychiatric medicines, antihistamines and/or hormonal replacement.
• • Patients who are already regularly using topical drops or ointments.