Pain Type and Interstitial Cystitis/Bladder Pain Syndrome Treatment

Launched by VANDERBILT UNIVERSITY MEDICAL CENTER · Feb 29, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how different types of pain affect the way people respond to two common treatments for Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS), which is a condition that causes severe pain in the bladder and pelvic area. The treatments being tested are pelvic floor physical therapy (PT) and cognitive-behavioral therapy (CBT). The researchers believe that people with IC/BPS may experience different types of pain, which could influence how well these therapies work for them.

To participate in this trial, you need to be at least 18 years old and have a confirmed diagnosis of IC/BPS. The study is currently looking for participants, and you will be able to take part if you can commit to the study duration and understand the process. Throughout the trial, participants will receive the therapies and share their experiences to help researchers learn more about how these treatments can be tailored to individuals based on their specific pain characteristics. It's important to note that certain health conditions or recent treatments may exclude you from participating, so be sure to discuss your medical history with the study team.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 18 years of age or older;
• • Diagnosis of IC/BPS as indicated by structured assessments;
• • Capable of giving written informed consent;
• • Able to enroll for the duration of the study period;
• Exclusion Criteria:
• • Comorbid neurological conditions including spinal cord injury or systematic neurologic illnesses, or central nervous system diseases such as brain tumor or stroke;
• • Current or history of diagnosis of primary psychotic or major thought disorder within the past five years;
• • Hospitalization for psychiatric reasons other than suicidal ideation, homicidal ideation, and/or PTSD (within the past 5 years);
• • Psychiatric or behavioral conditions in which symptoms are unstable or severe (e.g. current delirium, mania, psychosis, active suicidal ideation, homicidal ideation, substance abuse dependency) reported within the past six months;
• • Non-English speaking;
• • Presenting symptoms at time of screening that would interfere with participation, specifically active suicidal ideation with intent to harm oneself or active delusional or psychotic thinking;
• • Difficulties or limitations communicating over the telephone or via teleconferencing systems;
• • Any planned life events that would interfere with participating in the key elements of the study;
• • Any major active medical issues that could preclude participation;
• • Currently pregnant;
• • Currently being treated for cancer;
• • Cancer-related pain;
• • Recently or actively participating in treatment similar to those being investigated (e.g. individual psychotherapy or pelvic floor pt).