Evaluating the Effect of Injectable Platelet-rich Fibrin on Accelerating Orthodontic Tooth Movement

Launched by HAMA UNIVERSITY · Mar 4, 2024

Keywords

ClinConnect Summary

This clinical trial is studying whether an injection of a substance called platelet-rich fibrin (PRF) can help speed up the movement of teeth during orthodontic treatment. The goal is to reduce the overall time patients spend in braces, making the treatment process quicker and more comfortable. Researchers are currently looking for participants who are between 18 and 26 years old, have specific types of misaligned teeth that may require the removal of a tooth, and have good oral health.

If you're interested in joining the trial, you should be aware that there are some health criteria. For example, you should not have any serious health conditions that could affect your teeth moving, and you shouldn’t have had prior orthodontic treatments. Participants can expect to receive the injectable treatment and will need to attend regular follow-up appointments to monitor their progress. This trial is an exciting opportunity to potentially improve orthodontic care for many patients!

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • The patient's age (18-26). Severe or very severe irregularity of the upper incisors greater than (7 mm) according to Little's index, so it is recommended to extract the upper first premolar.
• • Class I or Class II malocclusion, first model according to Angle, with skeletal class I or II and a normal or mild vertical growth pattern.
• • All permanent upper teeth, up to the first molar, are present, with the possibility of attaching brackets to all teeth in a correct position.
• • The patient has good oral health.
• Exclusion Criteria:
• • • The presence of any systemic disease that affects orthodontic dental movement.
• • Severe malalignment of one of the teeth (palatal quadrant, ectopic canine, ectopic premolar).
• • The patient has undergone previous orthodontic treatment.
• • The patient is subject to any drug treatment that may affect orthodontic dental movement (cortisone, non-steroidal anti-inflammatory drugs).
• • The patient has poor oral health.
• • Commitment to periodic follow-up appointments.