NIDCD Otolaryngology Clinical Protocol Biospecimen Bank

Launched by NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS (NIDCD) · Mar 8, 2024

Keywords

ClinConnect Summary

The NIDCD Otolaryngology Clinical Protocol Biospecimen Bank is a study aimed at understanding disorders of the head and neck, which can affect hearing, balance, taste, and other important functions. Researchers want to collect biological samples, like tissue and blood, from individuals who have these conditions to improve how we diagnose and treat them. If you or a loved one has a disorder that affects hearing or other related abilities, you may be eligible to participate, as long as you can provide consent or have a guardian who can do so for minors.

Participants can expect to provide leftover tissue samples from routine medical care and may also be asked to give new samples, like blood or saliva. Those aged 3 years and older will undergo a physical exam, and additional tests may be required for adults, such as nasal secretions and small tissue biopsies. All samples collected could be used for important genetic testing. This study is currently recruiting participants of all ages and genders who meet specific health criteria, so if you think you might qualify, consider reaching out for more information.

Gender

ALL

Eligibility criteria

• • INCLUSION CRITERIA
• In order to be eligible to participate in this study, an individual must meet all of the following criteria:
• • Ability to provide their own consent, or for minors, a parent or guardian is able to consent on their behalf.
• • Ability of subject (or Legally Authorized Representative (LAR) to understand and the willingness to sign a written informed consent document.
• • Have a hearing, balance, smell, taste, voice, speech or language condition for which the subject is under clinical care or research purposes under a separate Review Board (IRB) approved protocol; OR be a healthy volunteer aged at least 3 years, enrolled on an approved research protocol.
• • EXCLUSION CRITERIA
• An individual who meets any of the following criteria will be excluded from participation in this study:
• • Have active symptomatic major organ disorders that would increase the risk of biopsy for research, including but not limited to bleeding disorders, ischemic heart disease, a recent myocardial infarction, active congestive heart failure or severe pulmonary dysfunction
• • Have specific medical condition, such as a bleeding tendency where additional biopsies or phlebotomy procedures may increase the subjects risk in participating. This will be determined at the discretion of the principal investigator.