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Search / Trial NCT06304259

Effect of Different Modalities of Cryotherapy on Post-Operative Pain in Patients With Symptomatic Irreversible Pulpitis

Launched by OCTOBER 6 UNIVERSITY · Mar 4, 2024

Trial Information

Current as of July 23, 2025

Not yet recruiting

Keywords

ClinConnect Summary

This clinical trial is studying how different types of cryotherapy, which is a cold treatment, can help reduce pain after dental procedures for patients with a specific condition called symptomatic irreversible pulpitis. The researchers want to compare two methods: one where cold saline is injected under the skin (submucosal cryotherapy) and another where cold is applied directly inside the tooth (intra-canal cryotherapy). The goal is to see which method can better manage pain after treating patients' teeth.

To participate in this trial, individuals must be over 18 years old and have a specific type of tooth pain due to a condition affecting the tooth’s pulp. They should also be able to commit to the study and agree to the terms after learning about it. Participants will be asked about their pain levels at various times after the treatment, and some tests will be done to measure pain-related substances. This research is important because it could help improve pain management for patients undergoing dental treatments.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Older than age of 18 years
  • Participants willing to commit for the entire period of the trial and Both genders
  • agreed to sign the written consent after full explanation of the study
  • Having a mandibular single rooted premolar tooth with vital pulp
  • These patients were also suffering from symptoms of symptomatic irreversible pulpitis and apical periodontitis, intermittent or continuous sharp pain that lasts longer after removal of the stimulus. on the basis of the clinical symptoms of severe preoperative pain (visual analogue scale)
  • Exclusion Criteria:
  • Vulnerable group; prisoners, pregnant females, mentally ill, etc...
  • Teeth with open apices
  • A previous root canal treatment
  • Sinus tracts
  • Presence of periodontal pockets \>3 mm in the affected tooth

About October 6 University

October 6 University is a prestigious educational institution dedicated to advancing medical research and clinical trials. With a strong emphasis on innovation and excellence, the university fosters a collaborative environment that integrates cutting-edge scientific research with practical clinical applications. Its commitment to improving healthcare outcomes is reflected in its comprehensive approach to clinical trials, where it engages in rigorous methodologies and ethical standards to ensure the safety and efficacy of new treatments. Through its dedicated research facilities and highly qualified personnel, October 6 University aims to contribute significantly to the global medical community and enhance patient care.

Locations

Cairo, , Egypt

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported