Partial Versus Total Knee Replacement in Bicompartmental Gonarthrosis (Medial and Patellofemoral): Prospective Functional Assessment Study
Launched by I.R.C.C.S OSPEDALE GALEAZZI-SANT'AMBROGIO · Mar 5, 2024
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying two different types of knee replacement surgeries to find out which one helps patients recover better after surgery. Specifically, it's comparing partial knee replacement (where only part of the knee is replaced) with total knee replacement (where the entire knee joint is replaced). The researchers will look at the patients' recovery by using a questionnaire that measures how well they can function after their surgery, focusing on their progress one month after the operation.
To be eligible for this study, participants should be adults aged 40 to 85 who have a specific type of knee disease called medial gonarthrosis, which causes pain and stiffness in the knee. They should also have certain symptoms related to their knee condition. Participants will be divided into two groups, with one group receiving partial knee replacement and the other receiving total knee replacement. Throughout the study, participants will be asked to fill out forms about their recovery and any changes they notice in their knee function. It's important to note that some individuals, such as those with certain health issues or those outside the age range, will not be eligible to participate.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Grade 3-4 sec Kellgren-Lawrence medial gonarthrosis
- • Patellar symptoms
- • Primary gonarthrosis
- • Patients with ligament integrity
- • Age between 40 and 85 years inclusive
- • Signing of the Informed Consent and consent to cooperate in all study procedures.
- Exclusion Criteria:
- • Cognitive impairment
- • Psychiatric disorders
- • Neuromuscular disorders
- • Age \> 85 years and \<40 years
- • Lateral gonarthrosis grade 4 sec Kellgren-Lawrence
- • Secondary medial gonarthrosis
- • Revisions
- • Minors
- • Pregnant women self-declaration
About I.R.C.C.S Ospedale Galeazzi Sant'ambrogio
The I.R.C.C.S. Ospedale Galeazzi-Sant'Ambrogio is a leading clinical research institute and hospital in Italy, renowned for its commitment to advancing medical science through innovative research and high-quality patient care. As a designated Institute of Hospitalization and Care of Scientific Relevance (I.R.C.C.S.), it focuses on translational research that bridges the gap between laboratory findings and clinical applications. The facility is equipped with state-of-the-art technology and a multidisciplinary team of experts, enabling it to conduct a wide range of clinical trials aimed at improving treatment outcomes across various medical fields. Its dedication to ethical practices and patient safety ensures that all research activities align with the highest international standards.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Milan, Italia, Italy
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported