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Search / Trial NCT06307704

Lung US for PEEP Optimization in Robotic Radical Prostatectomy or Cystectomy Patients

Launched by NAZMY EDWARD SEIF · Mar 11, 2024

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Radical Cystectomy Radical Prostatectomy Robotic Anesthesia Lung Ultrasound Positive End Expiratory Pressure

ClinConnect Summary

This clinical trial is studying how well a technique called lung ultrasound can help improve breathing in patients undergoing robotic surgery for prostate or bladder cancer. The goal is to find the best way to adjust a breathing support method known as Positive End Expiratory Pressure (PEEP) during surgery, which can help prevent lung problems after the operation. Using lung ultrasound is a quick and cost-effective approach that may lead to better oxygen levels and fewer breathing complications without causing issues with blood pressure.

To participate in this study, patients should be between the ages of 65 and 75, have normal or mild respiratory conditions, and be classified as ASA I, II, or III (which indicates different levels of health before surgery). However, those with severe obesity or significant lung or heart issues are not eligible. Participants can expect to receive personalized care during their surgery, including adjustments to their breathing support based on ultrasound findings. This trial is currently seeking volunteers, and it's an exciting opportunity to contribute to improving surgical care for patients with prostate and bladder cancer.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • ASA I, II \& III.
  • Normal respiratory functions or mild lung disease.
  • Exclusion Criteria:
  • BMI more than 40.
  • Moderate to severe obstructive pulmonary disease (FEV1 \< 80% of predicted).
  • Moderate to severe restrictive pulmonary disease (TLC \< 70% of predicted).
  • Severe pulmonary hypertension (mean PAP\>55).
  • Previous lung surgery.
  • Decompensated cardiac disease (NYHA 3 or 4).
  • Patients who received invasive mechanical ventilation within the last 30 days before surgery.

About Nazmy Edward Seif

Nazmy Edward Seif is a dedicated clinical trial sponsor committed to advancing medical research and innovation. With a focus on developing novel therapeutic solutions, the organization collaborates with leading healthcare professionals and institutions to design and execute rigorous clinical studies. Emphasizing patient safety and ethical standards, Nazmy Edward Seif strives to facilitate the seamless transition of groundbreaking therapies from the laboratory to clinical practice, ultimately aiming to improve patient outcomes and enhance public health.

Locations

Cairo, , Egypt

Patients applied

0 patients applied

Trial Officials

Ashgan R Ali, MD

Study Chair

Kasr Al-Ainy Hospital, Faculty of Medicine, Cairo University

Nazmy S Mikhael, MD

Principal Investigator

Kasr Al-Ainy Hospital, Faculty of Medicine, Cairo University

Mustafa E Mohamed, MD

Study Director

Kasr Al-Ainy Hospital, Faculty of Medicine, Cairo University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported