Application of Concentrated Growth Factors in Alveolar Ridge Preservation

Launched by THE FOURTH AFFILIATED HOSPITAL OF ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE · Mar 7, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at a treatment called Concentrated Growth Factors (CGF) to see how it can help preserve and regenerate the tissues in the mouth after a tooth is extracted. When a tooth needs to be removed, it’s important to maintain the surrounding area (called the alveolar ridge) to support future dental work. The study aims to understand if using CGF during this process can improve the healing and preservation of both soft and hard tissues in the extraction site.

To participate in this study, you need to be between the ages of 25 and 45 and willing to sign a consent form. You should be scheduled for a tooth extraction and have no serious health issues, like diabetes or high blood pressure, that could complicate the surgery. Additionally, you should not be a smoker or have any active infections in the area where the tooth will be removed. If you join the trial, you can expect to undergo some examinations and receive the CGF treatment during your surgery, with careful follow-up to monitor your recovery. This study is currently recruiting participants, and your involvement could help improve future dental procedures for others.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Voluntarily participate in this trial and sign a written informed consent; Patients aged 25 ≤ age ≤ 45 years; The combination of intraoral and imaging examinations confirms that the affected tooth has no preservation value, requires tooth extraction, and the patient is willing to use site preservation; No progressive periodontal disease or acute apical periodontitis in the affected teeth; No long-term history of oral bisphosphonates; Non smoking patients； No systemic diseases such as diabetes and hypertension.
• Exclusion Criteria:
• • Patients who have difficulty tolerating surgery; Patients under 25 years old or above 45 years old; The whole body is accompanied by hypertension, diabetes and other serious systemic diseases, which need to be controlled by drugs; Patients who take oral medication that affects bone metabolism for at least one month due to the need for disease treatment; Patients who take medication that may affect platelet function was used within 3 months due to the need for disease treatment; Patients unable to undergo X-ray imaging examination due to pregnancy or preparation after site preservation surgery; Patients who Smoke; The apical and periodontal inflammation is in the acute phase (purulent phase) Regular follow-up or follow-up for more than 6 months is not allowed