Prevention of Caries in Head and Neck Cancer Survivors Who Underwent Radiotherapy
Launched by UNIVERSITY OF MILAN · Mar 5, 2024
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how to prevent tooth decay (caries) in people who have survived head and neck cancer and received radiation treatment. One of the problems these patients face after radiation is dry mouth, which makes it easier for cavities to form because there isn’t enough saliva to protect the teeth. The researchers want to find out if a special mousse containing calcium phosphate (CaP), when used along with fluoride treatments, can help strengthen teeth and reduce the risk of cavities.
If you are between the ages of 65 and 74 and have had radiation therapy for head and neck cancer, you may be eligible to participate. However, if you have no teeth left or are pregnant or breastfeeding, you would not qualify for this study. Participants will be randomly assigned to receive either the CaP and fluoride treatment or no treatment at all, and researchers will monitor the effectiveness of these treatments in preventing tooth decay. This study not only aims to help patients keep their teeth healthier but also to reduce complications that can arise from dental issues after cancer treatment.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • previous head and neck radiotherapy for oncological treatment
- Exclusion Criteria:
- • complete edentulism
- • pregnancy or breastfeeding
About University Of Milan
The University of Milan is a prestigious academic institution renowned for its commitment to advancing medical research and education. With a strong emphasis on interdisciplinary collaboration, the university actively sponsors clinical trials aimed at enhancing healthcare outcomes and fostering innovation in medical science. Its research initiatives are guided by a dedication to ethical standards and rigorous scientific methodologies, ensuring that trials not only contribute to the body of knowledge but also prioritize patient safety and well-being. Through its extensive network of researchers and clinicians, the University of Milan plays a pivotal role in translating scientific discoveries into practical applications that benefit communities both locally and globally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Milan, , Italy
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported