Prevalence and Risk Factor of Post-intensive Care Syndrome in Neuro-ICU

Launched by ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS · Mar 11, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at a condition called Post-intensive Care Syndrome (PICS), which can cause problems for patients after they leave the intensive care unit (ICU). PICS can lead to difficulties with physical function, thinking, and mental health, significantly affecting a person's quality of life. The study aims to understand how common PICS is among patients with neurological diseases, both when they leave the ICU and three months later. It will also try to figure out what factors might increase the risk of developing these symptoms.

To participate in this trial, individuals must have spent more than 24 hours in the ICU due to a neurological condition, and they must have received certain treatments, such as breathing support or other invasive therapies. The trial is open to all adults aged 65 to 74, as long as they or their designated support person do not oppose their participation. It's important to note that individuals who are minors, pregnant, or have severe pre-existing conditions may not be eligible. Participants can expect to be monitored for their symptoms and receive support throughout the study.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patient with \> 24h stay in intensive care unit
• • 2.Patients with a neurological disease affecting the central or peripheral nervous system, which is the reason for their hospitalization in intensive care.
• • 3. Patients who have received organ replacement or invasive therapy in the ICU (invasive or non-invasive ventilation, extra-renal purification, plasmapheresis, ventricular bypass, catecholamines).
• • 4. Non-opposition of the patient or of the trusted support person, or of a family member or close friend if the patient is unable to express non-opposition.
• Exclusion Criteria:
• • 1. Minors, protected adults and pregnant women
• • 2. Advanced neurodegenerative disease pre-existing prior to ICU admission
• • 3. Severe psychotic disorders pre-existing before admission to intensive care
• • 4. Patients whose neurological and psychiatric history is unknown prior to resuscitation