Microbiota Directed Food for Children With Severe Acute Malnutrition

Launched by INTERNATIONAL CENTRE FOR DIARRHOEAL DISEASE RESEARCH, BANGLADESH · Mar 11, 2024

Keywords

ClinConnect Summary

This clinical trial is focused on finding a new way to help children with severe acute malnutrition (SAM), a serious condition where children do not weigh enough for their height, affecting their growth and health. Researchers are testing a special type of food called microbiota-directed food (MDF), which is designed to improve the nutrition of these children. They want to see if this new food can help the children grow better and recover their health compared to standard treatment options.

To be part of this study, children aged 6 to 24 months who show signs of SAM (measured by specific weight and arm measurements) may be eligible, as long as they don’t have other serious medical issues. Parents or guardians will need to give their consent for their child to participate. Those who join the study can expect to receive either the new MDF or standard treatment, and researchers will monitor their growth and health throughout the trial. It's important to note that children who have allergies to certain foods or have recently taken antibiotics might not be able to participate. Overall, this trial aims to find better ways to support the health of children struggling with malnutrition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • The trial will include SAM children of either sex without any medical complication
• • Children aged between 6-\<24 months and with MUAC \<115 mm and/or WLZ \<-3
• Exclusion Criteria:
• • Children are not suffering from SAM.
• • Children with bi-pedal oedema.
• • Failed to obtain consent for study participation from parents or legal guardian.
• • Suffering from any chronic illness(es) or having severe anemia (\< 8 g/dl).
• • History of using antibiotics in the past seven days.
• • Children participating in other food intervention programs.
• • Children having known history of soy, peanut or milk protein allergy.
• • Children who will not pass appetite test.