Effects of the Postbiotic Blend ABB C3 on Adiposity and Glucose Metabolism in Children and Adolescents

Launched by FUNDACIÓ SANT JOAN DE DÉU · Mar 6, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how a special mixture called ABB C3 might help children and teenagers who are struggling with obesity. The study involves two groups: one group will take ABB C3, while the other group will receive a placebo (a treatment that doesn't have the active ingredient). Over three months, researchers will measure changes in body fat and blood health markers to see if ABB C3 is safe and effective in helping reduce body fat and improve health. After this initial period, participants can continue taking ABB C3 for an additional three months if they choose.

To participate, children and teenagers aged 8 to 18 who have obesity (which means their body weight is much higher than what is considered healthy for their age) may be eligible. However, some people won't be able to participate, such as those who have taken antibiotics or certain supplements recently, have specific chronic diseases, or are on medications that affect weight or appetite. Participants can expect regular check-ins and monitoring throughout the trial, helping researchers gather important information about the potential benefits of ABB C3 for improving health in young people.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age between 8- and 18-year-old
• • Obesity (BMI-SDS \> 2)
• Exclusion Criteria:
• • Antibiotic or pre/pro/postbiotic consumption 2 - 4 weeks prior to starting the study
• • Chronic diseases affecting glucose or lipid metabolism
• • Chronic medication affecting glucose or lipid metabolism, or inducing a pro-inflammatory state
• • History of bariatric surgery
• • Diabetes requiring insulin treatment
• • Severe intellectual disability
• • Pregnancy
• • Individuals taking medications that may alter appetite or weight, with a recent change in prescription within the last 3 months or anticipated changes during the 2 months of participation