Operative Hysteroscopy Versus Suction Curettage for Surgical Termination of Early Pregnancy Loss (Miscarriage)
Launched by ASSAF-HAROFEH MEDICAL CENTER · Mar 7, 2024
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at two different surgical methods to help women who have experienced an early pregnancy loss, commonly known as a miscarriage. The study involves 100 women who are up to 10 weeks pregnant and have chosen to undergo surgery after discussing other options. Participants will be randomly assigned to one of two groups: one will have a procedure called suction curettage, which is a standard method for removing tissue from the uterus, while the other group will undergo a newer technique called operative hysteroscopy, where a small device is used to remove tissue through a thin tube inserted into the uterus.
To be eligible for the trial, women must have experienced a miscarriage and be able to understand and give consent in Hebrew. They will have the surgery done under anesthesia in an outpatient setting, meaning they can go home the same day. After the procedure, they will be monitored for any immediate issues and will have follow-up calls to check on their recovery and future pregnancies. This study is important because it aims to find out which surgical method is safer and more effective for women who have suffered a miscarriage, helping to improve care and outcomes for future patients.
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • 1. Early pregnancy loss (miscarriage) up to 10 gestational weeks
- • 2. Able to give informed consent, and read/write in Hebrew
- Exclusion Criteria:
- • 1. Incomplete abortion presenting as heavy vaginal bleeding and dilated cervix
- • 2. Signs of infection and/or suspicion of septic abortion
- • 3. Previous diagnosis of Mullerian anomalies - septate, bicornuate, unicornuate or didelphi uterus
- • 4. Previous medical or surgical treatment in the current pregnancy
- • 5. Previous diagnosis or past surgery for intrauterine adhesions
- • 6. History of 2 or more prvious miscarriages
- • 7. History of 2 or more cesarean sections
- • 8. History of abdominal, vaginal or hysteroscopic myomectomy
About Assaf Harofeh Medical Center
Assaf-Harofeh Medical Center is a prominent healthcare institution located in Israel, renowned for its commitment to advancing medical research and improving patient care. As a key sponsor of clinical trials, the center focuses on a diverse range of therapeutic areas, leveraging its state-of-the-art facilities and interdisciplinary expertise to facilitate innovative studies. With a dedicated team of experienced researchers and clinicians, Assaf-Harofeh Medical Center is dedicated to fostering scientific breakthroughs that enhance treatment outcomes and contribute to the global medical community.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Be'er Ya'aqov, , Israel
Patients applied
Trial Officials
Noam Smorgick, MD
Principal Investigator
Assaf-Harofeh Medical Center
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported