Dairy Products to Your Gut and Brain

Launched by UNIVERSITY OF COPENHAGEN · Mar 7, 2024

Keywords

ClinConnect Summary

This clinical trial, titled "Dairy Products to Your Gut and Brain," is looking to see how different types of dairy—specifically fermented (like yogurt) and non-fermented (like regular milk)—affect bowel movements and brain function in healthy women who have bowel movements every other day or less. The researchers want to understand how our gut health might influence our brain health. They will also include a smaller study to compare women who have daily bowel movements with those who have fewer, to see how their gut and brain functions differ.

To join this study, participants must be healthy women aged between 16 and 40 who can commit to eating 300 grams of dairy each day and have bowel movements every second day or less. They should also have a smartphone and be comfortable understanding either Danish or English. It’s important to note that women who are pregnant, have certain medical conditions or take specific medications may not be eligible. Participants can expect to learn more about their gut and brain health while contributing to important research that could help others in the future.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Self-reported defecations every second day or less (intervention study only)
• • Willing to consume 300g milk/yogurt on a daily basis (intervention study only)
• • Owns a smartphone (iOS 11.0 and later or Android 5.0 and up)
• • Understand Danish or English
• Exclusion Criteria:
• • Current pregnancy or lactation
• • Dairy allergy or intolerance
• • Prior diagnosis of psychiatric or neurological illness
• • Current diagnosis of depression, anxiety, or stress
• • Prior diagnosis of metabolic or gastrointestinal disease (e.g., cardiovascular disease, diabetes, chronic constipation or diarrhea, inflammatory bowel diseases (IBD), celiac disease, small intestinal bacterial overgrowth (SIBO), cancer, etc.)
• • Use of antibiotics within the last month
• • Use of peroral corticosteroids (inhalers excepted)
• • Use of medications that alter normal bowel function and metabolism (e.g., laxatives, antidiarrheal agents, narcotics, diuretics, anticonvulsants, etc.)
• • Use of neuroactive medications (e.g., antidepressants, anxiolytics, anticonvulsants, antipsychotics, antiparkinsonian, etc.)
• • Concurrent participation in another trial
• • Any condition that makes the project responsible researcher doubt the feasibility of the volunteer´s participation